Test Description: The formalin paw test is used to assess acute and tonic nociceptive responses in mice.
A metal band is placed around the left hind paw of each mouse and 20 Ál of 5% formalin
is subcutaneously injected in the dorsal surface of the left hind paw. Mice are
individually housed in cylindrical chambers for 45 minutes. A computer records
flinches per minute, total flinches for phase I (acute phase = first 8 minutes),
and total flinches for phase II (tonic phase between 20 - 40 minutes) through an