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Test Description: A large arena (40 cm x 40 cm) with infrared beams at three different levels is used to record rearing, hole poke, and locomotor activity. The animal is placed in the center and its activity is measured for 20 minutes. Data from this test is analyzed in five, 4-minute intervals. The total distance traveled (cm), vertical movement number (rearing), number of hole pokes, and the center:total distance ratio are then graphed.








Results Data
GenotypeMedian Rearing ActivityMedian Hole Poke ActivityMedian Normalized Slope**
+/+ (n=8)39.029.0-2.25
+/- (n=0)   
-/- (n=8)46.532.0-1.14
** Normalized slope is based on total distance traveled.


Genotype Mouse Label % of Total Distance Normalized
Slope
Interval 1
(4 min)
Interval 2
(8 min)
Interval 3
(12 min)
Interval 4
(16 min)
Interval 5
(20 min)
hom M-161 25.4 20.41 15.26 18.77 20.16 -1.21
hom F-163 21.18 28.42 16.72 18.95 14.73 -2.24
hom M-167 21.24 19.22 22.37 19.22 17.94 -0.66
hom M-173 25.94 31.3 15.4 14.33 13.03 -4.28
hom M-182 24.31 20.53 26.86 11.85 16.45 -2.44
hom F-200 17.82 24.28 20.05 23.47 14.37 -0.77
hom F-211 19.98 21.44 20.03 24.05 14.49 -0.84
hom F-223 20.5 25.62 17.8 16.16 19.92 -1.06
(hom)   Slope  Median:   -1.13
Mean:   -1.69
wt M-165 23.5 19.72 18.8 15.84 22.14 -0.66
wt M-179 16.54 23.97 22.72 20.66 16.11 -0.42
wt F-183 27.42 20.87 18.6 10.36 22.75 -1.99
wt F-198 29.26 18.35 30.58 8.51 13.31 -4.17
wt M-203 24.36 24.28 16.93 19.52 14.91 -2.37
wt F-216 30.09 23.4 14.03 2.58 29.89 -2.12
wt F-225 38.31 28.21 22.69 10.21 0.58 -9.34
wt M-231 19.82 33.07 18.15 26.5 2.45 -4.13
(wt)   Slope  Median:   -2.24
Mean:   -3.15




  Openfield New Analysis data for Project: NIH-0778 - Results        Export Data to Spreadsheet
Mouse Label Genotype Age (days) SAMPLE SAMP DUR TOTAL DIST VACTV VMOVNO V TIME STRNO CTR DIST PSA PRI SAMP DUR PRI SAMP AUX SAMP DUR AUX SAMP
M-161 hom 79 1 240.0 819 17 11 6.7 29 186 P 4 5 0 0
M-161 hom 79 1 240.0 8 8 3.6 4 5
M-161 hom 79 2 240.0 658 54 21 15.0 40 322 P 4 5 0 0
M-161 hom 79 2 240.0 5 4 2.6 4 5
M-161 hom 79 3 240.0 492 56 18 16.4 28 146 P 4 5 0 0
M-161 hom 79 4 240.0 605 30 16 11.2 33 183 P 4 5 0 0
M-161 hom 79 5 240.0 7 5 4.2 4 5
M-161 hom 79 5 240.0 650 35 15 12.0 29 116 P 4 5 0 0
M-161 hom 79 4 240.0 11 8 8.0 4 5
M-161 hom 79 3 240.0 16 11 8.1 4 5
F-163 hom 79 1 240.0 4 4 1.5 4 5
F-163 hom 79 1 240.0 608 15 8 6.2 38 67 P 4 5 0 0
F-163 hom 79 2 240.0 16 11 9.6 4 5
F-163 hom 79 3 240.0 480 18 12 8.8 31 140 P 4 5 0 0
F-163 hom 79 5 240.0 423 13 8 8.7 26 74 P 4 5 0 0
F-163 hom 79 5 240.0 7 4 4.5 4 5
F-163 hom 79 4 240.0 10 8 8.2 4 5
F-163 hom 79 4 240.0 544 22 9 9.8 29 141 P 4 5 0 0
F-163 hom 79 3 240.0 2 2 0.3 4 5
F-163 hom 79 2 240.0 816 15 9 12.3 36 113 P 4 5 0 0
M-167 hom 79 1 240.0 11 10 5.1 4 5
M-167 hom 79 1 240.0 580 32 14 21.9 41 87 P 4 5 0 0
M-167 hom 79 4 240.0 525 29 14 14.2 39 101 P 4 5 0 0
M-167 hom 79 5 240.0 490 12 6 8.1 35 195 P 4 5 0 0
M-167 hom 79 5 240.0 20 15 11.9 4 5
M-167 hom 79 4 240.0 7 6 3.8 4 5
M-167 hom 79 3 240.0 611 40 14 22.5 35 124 P 4 5 0 0
M-167 hom 79 3 240.0 20 12 5.5 4 5
M-167 hom 79 2 240.0 525 25 10 14.2 37 138 P 4 5 0 0
M-167 hom 79 2 240.0 13 10 3.4 4 5
M-173 hom 79 1 240.0 0 0 0.0 4 5
M-173 hom 79 2 240.0 555 56 22 28.7 38 108 P 4 5 0 0
M-173 hom 79 5 240.0 2 1 0.2 4 5
M-173 hom 79 5 240.0 231 22 13 16.1 29 30 P 4 5 0 0
M-173 hom 79 4 240.0 0 0 0.0 4 5
M-173 hom 79 4 240.0 254 50 20 25.0 37 41 P 4 5 0 0
M-173 hom 79 3 240.0 3 1 0.2 4 5
M-173 hom 79 3 240.0 273 36 16 16.2 35 32 P 4 5 0 0
M-173 hom 79 2 240.0 0 0 0.0 4 5
M-173 hom 79 1 240.0 460 40 21 20.8 31 93 P 4 5 0 0
M-182 hom 79 1 240.0 1 1 0.4 4 5
M-182 hom 79 1 240.0 238 0 0 0.0 45 58 P 4 5 0 0
M-182 hom 79 2 240.0 201 9 4 2.5 31 74 P 4 5 0 0
M-182 hom 79 3 240.0 8 7 3.7 4 5
M-182 hom 79 5 240.0 3 2 0.6 4 5
M-182 hom 79 5 240.0 161 6 6 4.9 38 46 P 4 5 0 0
M-182 hom 79 4 240.0 116 1 1 0.7 22 83 P 4 5 0 0
M-182 hom 79 4 240.0 25 15 14.0 4 5
M-182 hom 79 3 240.0 263 15 7 6.3 41 123 P 4 5 0 0
M-182 hom 79 2 240.0 12 8 10.2 4 5
F-200 hom 78 1 240.0 5 4 1.3 4 5
F-200 hom 78 3 240.0 621 14 10 7.7 31 178 P 4 5 0 0
F-200 hom 78 5 240.0 445 20 8 5.5 49 189 P 4 5 0 0
F-200 hom 78 5 240.0 1 1 0.2 4 5
F-200 hom 78 4 240.0 727 14 8 7.5 32 247 P 4 5 0 0
F-200 hom 78 4 240.0 19 11 4.3 4 5
F-200 hom 78 3 240.0 7 5 1.8 4 5
F-200 hom 78 2 240.0 752 29 15 13.3 32 227 P 4 5 0 0
F-200 hom 78 2 240.0 7 6 1.4 4 5
F-200 hom 78 1 240.0 552 9 6 6.0 47 45 P 4 5 0 0
F-211 hom 78 1 240.0 5 4 2.5 4 5
F-211 hom 78 5 240.0 3 3 2.2 4 5
F-211 hom 78 5 240.0 317 6 3 2.2 31 62 P 4 5 0 0
F-211 hom 78 4 240.0 9 8 7.9 4 5
F-211 hom 78 4 240.0 526 17 9 8.8 31 110 P 4 5 0 0
F-211 hom 78 3 240.0 16 8 16.2 4 5
F-211 hom 78 3 240.0 438 10 6 3.7 23 75 P 4 5 0 0
F-211 hom 78 2 240.0 9 8 3.9 4 5
F-211 hom 78 2 240.0 469 13 8 6.4 30 105 P 4 5 0 0
F-211 hom 78 1 240.0 437 7 4 2.1 21 77 P 4 5 0 0
F-223 hom 77 1 240.0 9 6 8.0 4 5
F-223 hom 77 2 240.0 10 6 4.0 4 5
F-223 hom 77 3 240.0 369 18 8 10.0 42 76 P 4 5 0 0
F-223 hom 77 5 240.0 413 7 3 3.7 36 58 P 4 5 0 0
F-223 hom 77 5 240.0 15 11 6.4 4 5
F-223 hom 77 4 240.0 16 12 12.1 4 5
F-223 hom 77 4 240.0 335 14 10 14.3 38 92 P 4 5 0 0
F-223 hom 77 2 240.0 531 17 9 14.3 30 52 P 4 5 0 0
F-223 hom 77 3 240.0 8 7 5.4 4 5
F-223 hom 77 1 240.0 425 5 4 3.4 36 53 P 4 5 0 0
M-165 wt 79 1 240.0 485 13 7 5.5 34 195 P 4 5 0 0
M-165 wt 79 5 240.0 9 8 4.0 4 5
M-165 wt 79 5 240.0 457 26 14 11.6 39 240 P 4 5 0 0
M-165 wt 79 4 240.0 327 14 8 5.2 39 172 P 4 5 0 0
M-165 wt 79 3 240.0 388 10 5 4.1 28 196 P 4 5 0 0
M-165 wt 79 4 240.0 9 7 4.4 4 5
M-165 wt 79 3 240.0 12 11 5.4 4 5
M-165 wt 79 2 240.0 407 19 8 7.4 32 214 P 4 5 0 0
M-165 wt 79 2 240.0 23 21 9.9 4 5
M-165 wt 79 1 240.0 11 10 4.4 4 5
M-179 wt 79 1 240.0 0 0 0.0 4 5
M-179 wt 79 5 240.0 10 11 7.8 4 5
M-179 wt 79 5 240.0 336 27 9 14.6 33 108 P 4 5 0 0
M-179 wt 79 4 240.0 9 7 5.1 4 5
M-179 wt 79 4 240.0 431 13 5 7.5 31 99 P 4 5 0 0
M-179 wt 79 3 240.0 474 26 12 13.1 39 74 P 4 5 0 0
M-179 wt 79 3 240.0 1 1 0.1 4 5
M-179 wt 79 2 240.0 21 21 9.9 4 5
M-179 wt 79 1 240.0 345 11 5 4.8 33 55 P 4 5 0 0
M-179 wt 79 2 240.0 500 21 9 10.1 36 80 P 4 5 0 0
F-183 wt 79 1 240.0 18 11 6.5 4 5
F-183 wt 79 4 240.0 4 4 1.5 4 5
F-183 wt 79 5 240.0 49 18 46.6 4 5
F-183 wt 79 5 240.0 472 8 5 5.5 32 180 P 4 5 0 0
F-183 wt 79 4 240.0 215 20 7 7.4 31 58 P 4 5 0 0
F-183 wt 79 3 240.0 386 14 9 10.9 35 152 P 4 5 0 0
F-183 wt 79 3 240.0 19 14 6.9 4 5
F-183 wt 79 2 240.0 15 10 9.4 4 5
F-183 wt 79 2 240.0 433 14 10 7.9 28 143 P 4 5 0 0
F-183 wt 79 1 240.0 569 18 10 9.1 33 128 P 4 5 0 0
F-198 wt 78 1 240.0 1 1 0.2 4 5
F-198 wt 78 1 240.0 244 3 3 0.3 37 33 P 4 5 0 0
F-198 wt 78 5 240.0 2 1 1.9 4 5
F-198 wt 78 5 240.0 111 0 0 0.0 35 55 P 4 5 0 0
F-198 wt 78 4 240.0 71 1 1 0.4 29 35 P 4 5 0 0
F-198 wt 78 4 240.0 2 1 0.4 4 5
F-198 wt 78 3 240.0 255 2 2 1.5 33 87 P 4 5 0 0
F-198 wt 78 3 240.0 4 4 1.7 4 5
F-198 wt 78 2 240.0 153 1 1 0.6 24 10 P 4 5 0 0
F-198 wt 78 2 240.0 0 0 0.0 4 5
M-203 wt 78 1 240.0 16 10 7.7 4 5
M-203 wt 78 2 240.0 601 28 12 18.6 31 196 P 4 5 0 0
M-203 wt 78 1 240.0 603 28 12 13.4 41 104 P 4 5 0 0
M-203 wt 78 2 240.0 14 11 9.5 4 5
M-203 wt 78 3 240.0 4 3 3.4 4 5
M-203 wt 78 5 240.0 9 6 7.0 4 5
M-203 wt 78 5 240.0 369 45 17 21.8 32 105 P 4 5 0 0
M-203 wt 78 4 240.0 0 0 0.0 4 5
M-203 wt 78 4 240.0 483 64 28 32.5 35 219 P 4 5 0 0
M-203 wt 78 3 240.0 419 50 20 28.0 41 161 P 4 5 0 0
F-216 wt 78 1 240.0 594 12 9 4.9 26 12 P 4 5 0 0
F-216 wt 78 1 240.0 2 2 1.1 4 5
F-216 wt 78 5 240.0 590 15 7 9.2 35 96 P 4 5 0 0
F-216 wt 78 3 240.0 277 8 6 3.8 27 10 P 4 5 0 0
F-216 wt 78 5 240.0 12 11 9.4 4 5
F-216 wt 78 4 240.0 0 1 0.5 4 5
F-216 wt 78 4 240.0 51 0 0 0.0 17 3 P 4 5 0 0
F-216 wt 78 3 240.0 4 3 1.4 4 5
F-216 wt 78 2 240.0 462 18 10 7.0 24 35 P 4 5 0 0
F-216 wt 78 2 240.0 9 8 7.7 4 5
F-225 wt 77 1 240.0 9 8 5.2 4 5
F-225 wt 77 5 240.0 0 0 0.0 4 5
F-225 wt 77 5 240.0 10 0 0 0.0 30 0 P 4 5 0 0
F-225 wt 77 4 240.0 0 0 0.0 4 5
F-225 wt 77 4 240.0 176 6 4 3.2 33 29 P 4 5 0 0
F-225 wt 77 3 240.0 9 9 7.0 4 5
F-225 wt 77 3 240.0 391 4 3 2.8 35 122 P 4 5 0 0
F-225 wt 77 1 240.0 660 6 5 2.2 32 101 P 4 5 0 0
F-225 wt 77 2 240.0 486 13 8 6.5 31 199 P 4 5 0 0
F-225 wt 77 2 240.0 13 11 6.2 4 5
M-231 wt 77 1 240.0 0 0 0.0 4 5
M-231 wt 77 5 240.0 22 5 4 1.2 15 0 P 4 5 0 0
M-231 wt 77 5 240.0 0 0 0.0 4 5
M-231 wt 77 4 240.0 238 41 13 16.5 37 18 P 4 5 0 0
M-231 wt 77 4 240.0 0 0 0.0 4 5
M-231 wt 77 3 240.0 163 11 7 8.1 31 41 P 4 5 0 0
M-231 wt 77 3 240.0 0 0 0.0 4 5
M-231 wt 77 1 240.0 178 10 4 2.8 31 23 P 4 5 0 0
M-231 wt 77 2 240.0 0 0 0.0 4 5
M-231 wt 77 2 240.0 297 21 10 14.6 35 32 P 4 5 0 0
 


Copyright 2005 by Lexicon Genetics Incorporated
Lexicon Phenotypic Analysis software version 05.05.00.05