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Genetics Project Specific Summary : NIH-0719
Summary of X-linked Gene Distributions for Sex by Genotype
Progeny
Sex
Agouti F1 (M chimera x wt)
Progeny
Sex
F1a (F het x wt)
wt
het
wt
het
hemi
M
12
0
M
27
N/A
28
F
2
11
F
22
21
N/A

Genetics Information

Targeted or gene trap mutations are generated in strain129SvEvBrd-derived embryonic stem (ES) cells. The chimeric mice are bred to C57BL/6J albino mice to generate F1 female heterozygous animals.These progeny are crossed to hybrid 129SvEvBrd / C57 F1 mice, derived from crossing 129SvEvBrd mice to C57BL/6J mice, to generateF1A wild-type, female heterozygous, and male hemizygous mice. Level I phenotypic analysis is performed on mice from this generation.


   wt het hom Total
Observed 14 14 31 59
Expected 14.75 29.5 14.75 59
Chi-Sq.= 26.08 Significance= 2.1717008E-6 (hom/n)= 0.53 Avg. Litter Size= 8


Copyright 2005 by Lexicon Genetics Incorporated
Lexicon Phenotypic Analysis software version 05.05.00.05