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Gene Summary for NIH-0719
Functional Category: enzyme-sulfotransferase
Cell Location: integral membrane
OST #:
Mouse Nucleotide Accession #: NM_015819
Human Nucleotide Accession #: NM_147175

Summary:
The targeted mouse gene is heparan sulfate 6-O-sulfotransferase 2 (Hs6st2), the ortholog of human HS6ST2. The protein has also been referred to as hypothetical protein FLJ32144 and HS6ST-2.

Phenotypic Summary for NIH-0719
No Notable Phenotype

Mouse Gene Sequence Information
Nucleotide Reference: NM_015819 Mus musculus heparan sulfate 6-O-sulfotransferase 2 (Hs6st2), mRNA
Protein Reference: NP_056634 heparan sulfate 6-O-sulfotransferase 2 [Mus musculus]
Entrez Gene: 50786

Human Gene Sequence Information
Nucleotide Reference: NM_147175 Homo sapiens heparan sulfate 6-O-sulfotransferase 2 (HS6ST2), transcript variant S, mRNA
Protein Reference: NP_671703 heparan sulfate 6-O-sulfotransferase 2 [Homo sapiens]
Entrez Gene: 90161

Mutation Information
Mutation Type: Homologous Recombination (standard)
Description: Coding exon 1 was targeted (NCBI NM_015819).


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Lexicon Phenotypic Analysis software version 05.05.00.05