| Gene Summary for NIH-0516 |
|---|
| Functional Category: |
signal transduction-receptor-gpcr |
| Cell Location: |
integral membrane |
| OST #: |
|
| Mouse Nucleotide Accession #: |
AK021164 |
| Human Nucleotide Accession #: |
NM_003508 |
|
|
| Summary: |
| The gene of interest is mouse Fzd9 (frizzled homolog 9 [Drosophila]), ortholog of human FZD9. Aliases include mfz9 and FZD3. |
|
| Phenotypic Summary for NIH-0516 |
|---|
| The male homozygous mutant mice exhibited signs of growth retardation, including decreased mean body weight and length, total tissue mass, lean body mass, and bone mineral-related measurements. Disruption of the target gene was confirmed by Southern hybridization analysis. |
| Mouse Gene Sequence Information |
|---|
 |
Nucleotide Reference: |
AK021164 ACCESSION:AK021164 NID:12861957 Mus musculus Mus musculus 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130077B15 product:frizzled homolog 9 (Drosophila), full insert sequence. gbhtc |
|
Protein Reference: |
Q9R216 ACCESSION:Q9R216 NID: Mus musculus (Mouse). Frizzled 9 precursor (Frizzled-9) (Fz-9) (mFz9) (mFz3). MOUSESPTRNRDB |
|
Entrez Gene: |
14371 |
| Human Gene Sequence Information |
|---|
|
Nucleotide Reference: |
NM_003508 ACCESSION:NM_003508 NID: gi 4503834 ref NM_003508.1 Homo sapiens frizzled homolog 9 (Drosophila) (FZD9), mRNA |
|
Protein Reference: |
O00144 ACCESSION:O00144 NID: Homo sapiens (Human). Frizzled 9 precursor (Frizzled-9) (Fz-9) (hFz9) (FzE6). HUMANSPTRNRDB |
|
Entrez Gene: |
8326 |
| Mutation Information |
|---|
| Mutation Type: |
Homologous Recombination (standard) |
| Description: |
The single exon (NCBI accession AK021164) was targeted. |
|
