Test Description: The tail suspension test is a procedure that has been developed as a model for depressive-like
behavior in rodents. In this particular setup, a mouse is suspended by its tail for 6 minutes,
and in response the mouse will struggle to escape from this position. After a certain period of
time the struggling of the mouse decreases and this is interpreted as a type of learned
helplessness paradigm. Animals with invalid data (i.e., climbed their tail during the testing
period) are excluded from analysis. |