Stress Induced Hyperthermia for Project: NIH-1790 Test Description: (SIH) is a measurement of autonomic hyperactivity induced by anxiety-provoking stimuli. The method involves taking two rectal body temperature measurements 10 minutes apart. SIH is determined by subtracting the basal body temperature (T1) from the stress-enhanced temperature (T2). The difference in delta values (T2 - T1 = deltaT) indicates the severity of autonomic hyperactivity or SIH. The rise in body temperature associated with SIH is a sign of anticipatory anxiety to the second rectal body temperature measurement. Lower deltaT values suggest decreased anxiety-like responses.

Results

Stress-Induced Hyperthermia Analysis data        Mouse Label Genotype Age (days) Stress Temperature Basal Temperature M-122 hom 63 37.2 35.9 M-127 hom 62 37.2 35.5 M-130 hom 62 37.1 35.7 M-135 hom 62 37.6 36.5 M-143 wt 62 37.2 35.4 M-150 wt 62 36.8 35.8 F-104 hom 67 0.0 35.2 F-105 hom 67 0.0 35.6 F-111 hom 67 0.0 35.5 F-115 hom 63 0.0 35.6 F-110 wt 67 0.0 35.1 F-132 wt 62 0.0 35.8

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