Symbol
Name
ID
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(36)
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Alleles
and
phenotypes
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All alleles(135) :
Targeted, knock-out(2)
Targeted, other(10)
Gene trapped(123)
| Homozygotes for targeted null mutations exhibit skeletal malformations, absence of floorplate and foregut, lung and anorectal defects, and altered commissural neuron guidance. Most mutants die before embryonic day 18.5. |
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Polymorphisms
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PCR(1)
SNPs within 2kb(944 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (99 records)
Data Summary:
Assays (24)
Results (138)
Tissues (102)
Images (44)
Theiler Stages: 12,13,15,16,17,19,20,21,22,23,25,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
4 |
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12 |
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RNA in situ |
18 |
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122 |
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Immunohistochemistry |
1 |
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2 |
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Northern blot |
1 |
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2 |
cDNA source data(46)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
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Molecular
reagents
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All nucleic(57)
Genomic(3)
cDNA(47)
Primer pair(5)
Other(2)
Antibodies(1)
Microarray probesets(3)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR007087 |
Zinc finger, C2H2-type |
| IPR013087 |
Zinc finger, C2H2-type/integrase, DNA-binding |
| IPR015880 |
Zinc finger, C2H2-like |
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References
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(Earliest)
J:4086
Hui CC et al.,
"A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene."
Nat Genet 1993 Mar;3(3):241-6
(Latest)
J:155992
Ching S et al.,
"Targeted disruption of Sonic Hedgehog in the mouse adrenal leads to adrenocortical hypoplasia."
Genesis 2009 Sep;47(9):628-37
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All references(155)
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Other
accession IDs
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MGD-MRK-10106, MGI:2138602
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Analysis Tools
MGI BioMart
