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Gas1 Gene Detail
 Symbol
Name
ID
Gas1
growth arrest specific 1
MGI:95655

Nomenclature History
Synonyms Gas-1
Genetic Map
Chromosome 13
37.0 cM, cytoband B3-C2
Detailed Genetic Map ± 1 cM
 
Mapping data( 10)

Sequence Map
Chr13:60275766-60278726 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Gas1 ± 2 cM)
Protein SuperFamily: growth arrest-specific protein 1, animal type
TreeFam: TF329660
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000033412 VEGA Gene Model | MGI Sequence Detail 2961 C57BL/6J ± Kb
transcript NM_008086 RefSeq | MGI Sequence Detail 3149 C57BL/6
polypeptide Q01721 UniProt | EBI | MGI Sequence Detail 343 Not Applicable
For the selected sequences
All sequences(22)
Alleles
and
phenotypes 		All alleles(2) : Targeted, knock-out(1) Targeted, other(1)
Mice homozygous for disruption of this gene experience background sensitive reduction of viability. Developmental defects are found in the eyes, cerebellum and limbs.
Polymorphisms RFLP(3) SNPs within 2kb(24 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (42 annotations)
Process axon guidance, camera-type eye development...
Component anchored to membrane, anchored to plasma membrane...
Function protein binding
External Resources: FuncBase
Expression Literature Summary: (18 records)
Data Summary: Assays (6)    Results (157)    Tissues (151)    Images (26)
Theiler Stages: 20,21,22,23,24,25,28
  Assay Type Assays   Results
      RT-PCR 1   46
      RNA in situ 5   111
cDNA source data(70)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(74) Genomic(1) cDNA(70) Primer pair(2) Other(1)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000052957
DoTS DT.101262279, DT.101310447, DT.493950
Consensus CDS Project CCDS26579.1
UniGene 22701
DFCI TC1576664, TC1592444, TC1696315
NIA Mouse Gene Index U034869
Entrez Gene 14451
VEGA Gene Model OTTMUSG00000033412
International Mouse Knockout Project Status Gas1
Protein
domains
InterPro ID Description
IPR016017 GDNF/GAS1
Graphical View of Protein Domain Structure
References
(Earliest) J:9302 Schneider C et al., "Genes specifically expressed at growth arrest of mammalian cells." Cell 1988 Sep 9;54(6):787-93
(Latest) J:151233 Trimarchi JM et al., "Identification of genes expressed preferentially in the developing peripheral margin of the optic cup." Dev Dyn 2009 Sep;238(9):2327-9
All references(36)
Other
accession IDs 		MGD-MRK-9985, MGD-MRK-9992, MGI:2145453
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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