Symbol
Name
ID
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Synonyms
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js, Sans
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(16)
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Alleles
and
phenotypes
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All alleles(4) :
Targeted, knock-out(1)
Spontaneous(3)
| Mutant homozygotes exhibit hyperactivity, head-tossing, circling behavior and profound deafness. Structurally, mutants display disorganized stereocilia of outer ear hair cells and degeneration of inner ear neuroepithelia. |
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Polymorphisms
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SNPs within 2kb(25 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (3 records)
Data Summary:
Assays (2)
Results (20)
Tissues (19)
Theiler Stages: 15,20,23,25,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
1 |
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17 |
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RNA in situ |
1 |
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3 |
cDNA source data(2)
External Resources:
Allen Brain Atlas
GEO
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Molecular
reagents
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All nucleic(4)
Genomic(1)
cDNA(2)
Primer pair(1)
Microarray probesets(1)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR001660 |
Sterile alpha motif SAM |
| IPR002110 |
Ankyrin repeat |
| IPR010993 |
Sterile alpha motif homology |
| IPR019157 |
High-temperature-induced dauer-formation protein-like |
| IPR020683 |
Ankyrin repeat-containing domain |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:13462
Dickie MM et al.,
"Jackson shaker, js"
Mouse News Lett 1967;36():39
(Latest)
J:135991
Lefevre G et al.,
"A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth."
Development 2008 Apr;135(8):1427-37
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All references(18)
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Other
accession IDs
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MGD-MRK-11532, MGI:96641
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