Symbol
Name
ID
|
|
|
Synonyms
|
6030440P17Rik, 8430406N05Rik, my
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(27)
|
Alleles
and
phenotypes
|
All alleles(5) :
Gene trapped(2)
Spontaneous(1)
Chemically induced(1)
Radiation induced(1)
| Mice homozygous for mutations at this locus display a significant amount of embryonic lethality due to hemorrhaging of embryonic blisters. Kidney development is severely affected and syndactyly is common. Phenotypes of homozygous mutants are indistinguishable from those of Fras1 homozygous mutant. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (3)
Phenotype Images (2)
|
|
Polymorphisms
|
SNPs within 2kb(1092 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (6 records)
Data Summary:
Assays (1)
Results (25)
Tissues (25)
Images (15)
Theiler Stages: 17,20,21,22,23,24
| |
Assay Type |
Assays |
|
Results |
| |
Immunohistochemistry |
1 |
|
25 |
cDNA source data(55)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
|
All nucleic(55)
cDNA(55)
Antibodies(1)
Microarray probesets(1)
|
Other database
links
|
|
Protein
domains
|
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:14847
Little CC et al.,
"The occurrence of two heritable types of abnormality among descendants of X-rayed mice"
Am J Roentgenol 1923;10():975-989
(Latest)
J:142530
Pitera JE et al.,
"Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli."
Hum Mol Genet 2008 Dec 15;17(24):3953-64
|
All references(22)
|
Other
accession IDs
|
MGD-MRK-12734, MGI:1918727, MGI:97248
|
