Symbol
Name
ID
|
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(24)
|
Alleles
and
phenotypes
|
All alleles(1) :
Targeted, knock-out(1)
| Homozygous null mutants are male sterile, failing to produce mature spermatozoa; peripheral nerves are abnormal, with thin and disorganized perineurial sheaths. High penetrance of pseudohermaphroditism observed on some mixed backgrounds. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
|
|
Polymorphisms
|
RFLP(1)
SNPs within 2kb(19 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (47 records)
Data Summary:
Assays (7)
Results (152)
Tissues (68)
Images (5)
Theiler Stages: 18,19,20,21,22,23,25,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
5 |
|
148 |
| |
RNA in situ |
1 |
|
3 |
| |
Northern blot |
1 |
|
1 |
cDNA source data(7)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(16)
Genomic(2)
cDNA(7)
Primer pair(4)
Other(3)
Microarray probesets(2)
|
Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR000320 |
Hedgehog, N-terminal signaling domain |
| IPR001657 |
Peptidase C46, hedgehog protein |
| IPR001767 |
Peptidase C46, hedgehog protein, hint region |
| IPR003586 |
Hedgehog/intein hint domain, C-terminal |
| IPR003587 |
Hedgehog/intein hint, N-terminal |
| IPR006141 |
Intein splicing site |
| IPR009045 |
Hedgehog/DD-peptidase, zinc-binding motif |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:16386
Echelard Y et al.,
"Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity."
Cell 1993 Dec 31;75(7):1417-30
(Latest)
J:154891
Hirose Y et al.,
"Hedgehog signal activation coordinates proliferation and differentiation of fetal liver progenitor cells."
Exp Cell Res 2009 Sep 10;315(15):2648-57
|
All references(66)
|
Other
accession IDs
|
MGD-MRK-8842, MGI:2146288
|
Analysis Tools
MGI BioMart
