About   Help   FAQ
Tour our new Quick Search
Scube1 Gene Detail
 Symbol
Name
ID
Scube1
signal peptide, CUB domain, EGF-like 1
MGI:1890616

Nomenclature History
Synonyms 7330410C13Rik, A630023E24Rik
Genetic Map
Chromosome 15
Syntenic
 
Mapping data( 3)
Sequence Map
Chr15:83435429-83555451 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; rat    (Mammalian Orthology)
TreeFam: TF351672
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000021075 VEGA Gene Model | MGI Sequence Detail 120023 C57BL/6J ± Kb
transcript NM_022723 RefSeq | MGI Sequence Detail 7824 C57BL/6
polypeptide Q6NZL8 UniProt | EBI | MGI Sequence Detail 1018 Not Applicable
For the selected sequences
All sequences(28)
Alleles
and
phenotypes 		All alleles(1) : Targeted, other(1)
Polymorphisms SNPs within 2kb(503 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(5)
Component extracellular region, membrane...
Function calcium ion binding
External Resources: MouseFunc
Expression Literature Summary: (2 records)
Data Summary: Assays (3)    Results (36)    Tissues (32)
Theiler Stages: 9,12,13,14,15,17,19,20,21,28
  Assay Type Assays   Results
      RNA in situ 1   25
      Northern blot 2   11
cDNA source data(43)
External Resources: Allen Brain Atlas  GENSAT  GEO 
Molecular
reagents 		All nucleic(45) Genomic(1) cDNA(43) Primer pair(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000016763
DoTS DT.101372684, DT.110826641, DT.55282914, DT.97350979, DT.97388540
UniGene 40393
DFCI TC1579913, TC1592696, TC1594999, TC1597901
NIA Mouse Gene Index U036480
Entrez Gene 64706
VEGA Gene Model OTTMUSG00000021075
International Mouse Knockout Project Status Scube1
Protein
domains
InterPro ID Description
IPR000152 EGF-type aspartate/asparagine hydroxylation site
IPR000742 EGF-like, type 3
IPR000859 CUB
IPR001881 EGF-like calcium-binding
IPR006209 EGF
IPR006210 EGF-like
IPR009030 Growth factor, receptor
IPR011641 GCC2/GCC3 domain
IPR013032 EGF-like region, conserved site
IPR013091 EGF calcium-binding
IPR018097 EGF-like calcium-binding, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:66050 Grimmond S et al., "Cloning, mapping, and expression analysis of a gene encoding a novel mammalian EGF-related protein (SCUBE1)" Genomics 2000 Nov 15;70(1):74-81
(Latest) J:136534 Tu CF et al., "Domain and functional analysis of a novel platelet-endothelial cell surface protein, SCUBE1." J Biol Chem 2008 May 2;283(18):12478-88
All references(3)
Other
accession IDs 		MGI:2146043, MGI:2444992
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
11/20/2009
MGI_4.31
Web browser compatibility 		The Jackson Laboratory