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Extl3 Gene Detail
 Symbol
Name
ID
Extl3
exostoses (multiple)-like 3
MGI:1860765


Nomenclature History
Synonyms 2900009G18Rik
Genetic Map
Chromosome 14
cytoband D1
 
Mapping data( 3)
Sequence Map
Chr14:65670901-65699312 bp, - strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: Caenorhabditis elegans hypothetical protein K01G5.6
TreeFam: TF314231
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000021978 Ensembl Gene Model | MGI Sequence Detail 28412 C57BL/6J ± Kb
transcript NM_018788 RefSeq | MGI Sequence Detail 5995 C57BL/6
polypeptide Q9WVL6 UniProt | EBI | MGI Sequence Detail 918 Not Applicable
For the selected sequences
All sequences(27)
Alleles
and
phenotypes
All alleles(6) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(4)
Mice homozygous for a null mutation display embryonic lethality during organogenesis and lack heparan sulfate derived disaccharides.
Polymorphisms SNPs within 2kb(192 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Component endoplasmic reticulum, integral to membrane...
Function glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity, manganese ion binding...
External Resources: FuncBase
Expression Literature Summary: (1 records)
Data Summary: Assays (1)    Results (56)    Tissues (43)
Theiler Stages: 19,20,22,24,28
  Assay Type Assays   Results
      RNA in situ 1   56
cDNA source data(131)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(133) cDNA(132) Primer pair(1)
Microarray probesets(2)
Other database
links
EC 2.4.1.223
Ensembl Gene Model ENSMUSG00000021978
DoTS DT.101131862, DT.50317061, DT.94163026
Consensus CDS Project CCDS27211.1
UniGene 103748
DFCI TC1580638, TC1601634, TC1655234, TC1657456
NIA Mouse Gene Index U035686
Entrez Gene 54616
International Mouse Knockout Project Status Extl3
Protein
domains
InterPro ID Description
IPR004263 Exostosin-like
IPR015338 EXTL2, alpha-1,4-N-acetylhexosaminyltransferase
Graphical View of Protein Domain Structure
References
(Earliest) J:60984 Ko MS et al., "Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development." Development 2000 Apr;127(8):1737-49
(Latest) J:148348 Takahashi I et al., "Important role of heparan sulfate in postnatal islet growth and insulin secretion." Biochem Biophys Res Commun 2009 May 22;383(1):113-8
All references(9)
Other
accession IDs
MGI:1925654, MGI:2145751

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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