Symbol
Name
ID
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Synonyms
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C6ST, C6ST-1, GST-0
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Genetic Map
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Chromosome 10
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cytoband C
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Mapping data(
2)
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Sequence Map
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Mammalian homology
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Sequences
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All sequences(20)
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Alleles and phenotypes
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All alleles(7) :
Targeted, knock-out(1)
Targeted, other(1)
Gene trapped(5)
| Homozygous mutation of this gene results in significantly reduced numbers of naive T lymphocytes in the spleen at 5-6 weeks of age. Brain development and morphology is normal in mutant animals but for some alleles behavioral abnormalities are seen. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
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Polymorphisms
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SNPs within 2kb(72 from dbSNP Build 128)
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Gene Ontology (GO) classifications
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Expression
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Literature Summary: (2 records)
Data Summary:
Assays (4)
Results (140)
Tissues (85)
Images (64)
Theiler Stages: 21,28
| |
Assay Type |
Assays |
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Results |
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RT-PCR |
2 |
|
40 |
| |
In situ reporter (knock in) |
1 |
|
96 |
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RNA in situ |
1 |
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4 |
cDNA source data(17)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
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Molecular reagents
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All nucleic(20)
cDNA(17)
Primer pair(3)
Microarray probesets(2)
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Other database links
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Protein domains
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| InterPro ID |
Description |
| IPR000863 |
Sulfotransferase domain |
| IPR016469 |
Carbohydrate sulfotransferase |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:47830
Uchimura K et al.,
"Mouse chondroitin 6-sulfotransferase: molecular cloning, characterization and chromosomal mapping."
Glycobiology 1998 May;8(5):489-96
(Latest)
J:133424
Akita K et al.,
"Expression of multiple chondroitin/dermatan sulfotransferases in the neurogenic regions of the embryonic and adult central nervous system implies that complex chondroitin sulfates have a role in neural stem cell maintenance."
Stem Cells 2008 Mar;26(3):798-809
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All references(7)
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