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Hs6st2 Gene Detail
 Symbol
Name
ID
Hs6st2
heparan sulfate 6-O-sulfotransferase 2
MGI:1354959


Nomenclature History
Synonyms 6OST2
Genetic Map
Chromosome X
cytoband A3.3
 
Mapping data( 2)
Sequence Map
ChrX:48740389-49035033 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
TreeFam: TF312835
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000017337 VEGA Gene Model | MGI Sequence Detail 294645 C57BL/6J ± Kb
transcript NM_001077202 RefSeq | MGI Sequence Detail 4234 C57BL/6
polypeptide Q80UW0 UniProt | EBI | MGI Sequence Detail 612 Not Applicable
For the selected sequences
All sequences(35)
Alleles
and
phenotypes
All alleles(4) : Targeted, knock-out(1) Targeted, other(2) Gene trapped(1)
Female homozygous or male hemizygous mice for a disruption in this gene display a normal phenotype.
Polymorphisms SNPs within 2kb(722 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process carbohydrate biosynthetic process
Component integral to membrane, membrane...
Function sulfotransferase activity, transferase activity...
External Resources: FuncBase
Expression Literature Summary: (6 records)
Data Summary: Assays (6)    Results (109)    Tissues (85)    Images (52)
Theiler Stages: 13,14,15,16,17,18,19,20,21,22,24,26
  Assay Type Assays   Results
      RT-PCR 3   14
      RNA in situ 3   95
cDNA source data(13)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(20) Genomic(3) cDNA(14) Primer pair(3)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000062184
DoTS DT.101249087, DT.101380112, DT.111027429, DT.527274
Consensus CDS Project CCDS40970.1
DFCI TC1577814, TC1591327, TC1650070, TC1707269
NIA Mouse Gene Index U041240, U359449
Entrez Gene 50786
VEGA Gene Model OTTMUSG00000017337
International Mouse Knockout Project Status Hs6st2
Protein
domains
InterPro ID Description
IPR005331 Sulfotransferase
IPR010635 Heparan sulphate 6-sulfotransferase
Graphical View of Protein Domain Structure
References
(Earliest) J:60682 Habuchi H et al., "The occurrence of three isoforms of heparan sulfate 6-O-sulfotransferase having different specificities for hexuronic acid adjacent to the targeted N-sulfoglucosamine." J Biol Chem 2000 Jan 28;275(4):2859-68
(Latest) J:136555 Sugaya N et al., "6-O-sulfation of heparan sulfate differentially regulates various fibroblast growth factor-dependent signalings in culture." J Biol Chem 2008 Apr 18;283(16):10366-76
All references(13)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
02/06/2010
MGI_4.32
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