Symbol
Name
ID
|
|
|
Synonyms
|
Pfrk
|
|
Genetic Map
|
|
Chromosome 9
|
cytoband E4
|
|
|
|
Mapping data(
2)
|
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(15)
|
Alleles
and
phenotypes
|
All alleles(3) :
Targeted, knock-out(2)
Targeted, other(1)
| Mice homozygous for disruptions in this gene display increased postnatal lethality. Of animals surving to mating age, males are fully fertile and females are infertile. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (2)
|
|
Polymorphisms
|
SNPs within 2kb(3 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (22 records)
Data Summary:
Assays (3)
Results (23)
Tissues (5)
Theiler Stages: 20,23,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
3 |
|
23 |
cDNA source data(8)
External Resources:
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(12)
cDNA(8)
Primer pair(4)
Microarray probesets(1)
|
Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR001766 |
Transcription factor, fork head |
| IPR011991 |
Winged helix repressor DNA-binding |
| IPR018122 |
Transcription factor, fork head, conserved site |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:48144
Treier M et al.,
"Multistep signaling requirements for pituitary organogenesis in vivo."
Genes Dev 1998 Jun 1;12(11):1691-704
(Latest)
J:153050
Bogani D et al.,
"Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination."
PLoS Biol 2009 Sep;7(9):e1000196
|
All references(33)
|
Other
accession IDs
|
MGI:2143241
|
Analysis Tools
MGI BioMart