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Apobec2 Gene Detail
 Symbol
Name
ID
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
MGI:1343178

Nomenclature History
Genetic Map
Chromosome 17
24.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 2)

Sequence Map
Chr17:48558556-48572053 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Apobec2 ± 2 cM)
TreeFam: TF331356
Sequences
Representative Sequences Length Strain/Species Flank
genomic 11811 NCBI Gene Model | MGI Sequence Detail 13498 C57BL/6J ± Kb
transcript NM_009694 RefSeq | MGI Sequence Detail 1218 C57BL/6
polypeptide Q9WV35 UniProt | EBI | MGI Sequence Detail 224 Not Applicable
For the selected sequences
All sequences(13)
Alleles
and
phenotypes 		All alleles(10) : Targeted, knock-out(1) Gene trapped(9)
Mice homozygous for disruptions in this gene display growth retardation and decreased bone mineralization and density.
Polymorphisms PCR(1) SNPs within 2kb(102 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process mRNA modification, mRNA processing...
Function catalytic activity, hydrolase activity...
External Resources: FuncBase
Expression Literature Summary: (1 records)
Data Summary: Assays (2)    Results (2)    Tissues (2)
Theiler Stages: 14,16
  Assay Type Assays   Results
      RT-PCR 1   1
      RNA in situ 1   1
cDNA source data(43)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(46) cDNA(44) Primer pair(2)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000040694
DoTS DT.535402
Consensus CDS Project CCDS28868.1
UniGene 281793
DFCI TC1579727
NIA Mouse Gene Index U037899
Entrez Gene 11811
International Mouse Knockout Project Status Apobec2
Protein
domains
InterPro ID Description
IPR007904 APOBEC-like, C-terminal
IPR013158 APOBEC-like, N-terminal
IPR016193 Cytidine deaminase-like
Graphical View of Protein Domain Structure
References
(Earliest) J:32731 Hirano K et al., "Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48." J Biol Chem 1996 Apr 26;271(17):9887-90
(Latest) J:118615 Terami H et al., "Efficient capture of cardiogenesis-associated genes expressed in ES cells." Biochem Biophys Res Commun 2007 Mar 30;355(1):47-53
All references(11)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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