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Klf3 Gene Detail
 Symbol
Name
ID
Klf3
Kruppel-like factor 3 (basic)
MGI:1342773


Nomenclature History
Synonyms 9930027G08Rik, BKLF, Bklf, Tef-2
Genetic Map
Chromosome 5
Syntenic
 
Mapping data( 2)
Sequence Map
Chr5:65194762-65221368 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
TreeFam: TF350556
Sequences
Representative Sequences Length Strain/Species Flank
genomic 16599 NCBI Gene Model | MGI Sequence Detail 26607 C57BL/6J ± Kb
transcript NM_008453 RefSeq | MGI Sequence Detail 2314 C57BL/6
polypeptide Q60980 UniProt | EBI | MGI Sequence Detail 344 Not Applicable
For the selected sequences
All sequences(36)
Alleles
and
phenotypes
All alleles(163) : Targeted, knock-out(1) Gene trapped(162)
Polymorphisms SNPs within 2kb(163 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(9)
Process regulation of transcription, transcription...
Component intracellular, nucleus...
Function DNA binding, metal ion binding...
External Resources: MouseFunc
Expression Literature Summary: (5 records)
Data Summary: Assays (7)    Results (131)    Tissues (90)    Images (9)
Theiler Stages: 2,3,4,5,17,21,23,24,28
  Assay Type Assays   Results
      RT-PCR 3   64
      RNA in situ 4   67
cDNA source data(11)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(15) cDNA(12) Primer pair(3)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000029178
DoTS DT.101369847, DT.110681434, DT.530499, DT.87071958, DT.91329134
PDB 1P7A, 1U85, 1U86
DFCI TC1578562, TC1602005, TC1613702, TC1620121
NIA Mouse Gene Index U005621, U322728
Entrez Gene 16599
International Mouse Knockout Project Status Klf3
Protein
domains
InterPro ID Description
IPR007087 Zinc finger, C2H2-type
IPR013087 Zinc finger, C2H2-type/integrase, DNA-binding
IPR015880 Zinc finger, C2H2-like
Graphical View of Protein Domain Structure
References
(Earliest) J:31944 Crossley M et al., "Isolation and characterization of the cDNA encoding BKLF/TEF-2, a major CACCC-box-binding protein in erythroid cells and selected other cells." Mol Cell Biol 1996 Apr;16(4):1695-705
(Latest) J:142311 Eaton SA et al., "A network of Kruppel-like Factors (Klfs). Klf8 is repressed by Klf3 and activated by Klf1 in vivo." J Biol Chem 2008 Oct 3;283(40):26937-47
All references(16)
Other
accession IDs
MGD-MRK-35910, MGI:107439, MGI:2141019, MGI:2441767

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/20/2009
MGI_4.31
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