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St3gal4 Gene Detail
 Symbol
Name
ID
St3gal4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
MGI:1316743


Nomenclature History
Synonyms Siat4c, ST3Gal IV
Genetic Map
Chromosome 9
cytoband A5.3
 
Mapping data( 2)
Sequence Map
Chr9:34854164-34924395 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: sialyltransferase
TreeFam: TF354325
Sequences
Representative Sequences Length Strain/Species Flank
genomic 20443 NCBI Gene Model | MGI Sequence Detail 70232 C57BL/6J ± Kb
transcript NM_009178 RefSeq | MGI Sequence Detail 2059 -
polypeptide Q91Y74 UniProt | EBI | MGI Sequence Detail 333 Not Applicable
For the selected sequences
All sequences(20)
Alleles
and
phenotypes
All alleles(8) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(6)
Polymorphisms SNPs within 2kb(213 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications(8)
Process protein amino acid glycosylation
Component Golgi apparatus, integral to Golgi membrane...
Function sialyltransferase activity, transferase activity...
External Resources: MouseFunc
Expression Literature Summary: (2 records)
Data Summary: Assays (2)    Results (40)    Tissues (15)
Theiler Stages: 12,22,28
  Assay Type Assays   Results
      RT-PCR 1   13
      Northern blot 1   27
cDNA source data(57)
External Resources: Allen Brain Atlas  GEO 
Molecular
reagents
All nucleic(59) cDNA(58) Primer pair(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000032038
UniGene 275973
DFCI TC1578703, TC1593390
NIA Mouse Gene Index U030659
Entrez Gene 20443
International Mouse Knockout Project Status St3gal4
Protein
domains
InterPro ID Description
IPR001675 Glycosyl transferase, family 29
IPR012163 Sialyltransferase
Graphical View of Protein Domain Structure
References
(Earliest) J:41275 Kono M et al., "Mouse beta-galactoside alpha 2,3-sialyltransferases: comparison of in vitro substrate specificities and tissue specific expression." Glycobiology 1997 Jun;7(4):469-79
(Latest) J:137041 Frommhold D et al., "Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation." J Exp Med 2008 Jun 9;205(6):1435-46
All references(15)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/20/2009
MGI_4.31
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The Jackson Laboratory