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Olr1 Gene Detail
 Symbol
Name
ID
Olr1
oxidized low density lipoprotein (lectin-like) receptor 1
MGI:1261434


Nomenclature History
Synonyms LOX-1, Scare1, SR-EI
Genetic Map
Chromosome 6
Syntenic
 
Mapping data( 2)
Sequence Map
Chr6:129435264-129457183 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
TreeFam: TF336674
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000034583 VEGA Gene Model | MGI Sequence Detail 21920 C57BL/6J ± Kb
transcript NM_138648 RefSeq | MGI Sequence Detail 3581 C57BL/6
polypeptide Q9EQ09 UniProt | EBI | MGI Sequence Detail 363 Not Applicable
For the selected sequences
All sequences(20)
Alleles
and
phenotypes
All alleles(2) : Targeted, knock-out(2)
Homozygous mutation of this gene results in no obvious phenotype.
Polymorphisms SNPs within 2kb(169 from dbSNP Build 128)   SNPs within 2kb including multiple locations(171)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process cell adhesion, immune response...
Component extracellular region, extrinsic to plasma membrane...
Function binding, low-density lipoprotein receptor activity...
External Resources: FuncBase
Expression Literature Summary: (2 records)
cDNA source data(7)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(8) cDNA(7) Other(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000030162
DoTS DT.101362207, DT.91283913, DT.99851250
Consensus CDS Project CCDS20588.1
UniGene 293626
DFCI TC1633099, TC1663157, TC1678207
NIA Mouse Gene Index U027917
Entrez Gene 108078
VEGA Gene Model OTTMUSG00000034583
International Mouse Knockout Project Status Olr1
Protein
domains
InterPro ID Description
IPR001304 C-type lectin
IPR016186 C-type lectin-like
IPR016187 C-type lectin fold
Graphical View of Protein Domain Structure
References
(Earliest) J:47339 Hoshikawa H et al., "High affinity binding of oxidized LDL to mouse lectin-like oxidized LDL receptor (LOX-1)." Biochem Biophys Res Commun 1998 Apr 28;245(3):841-6
(Latest) J:154572 Inomata Y et al., "Suppression of choroidal neovascularization in lectin-like oxidized low-density lipoprotein receptor type 1-deficient mice." Invest Ophthalmol Vis Sci 2009 Aug;50(8):3970-6
All references(14)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory