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Etv5 Gene Detail
 Symbol
Name
ID
Etv5
ets variant gene 5
MGI:1096867

Nomenclature History
Synonyms 1110005E01Rik, 8430401F14Rik, ERM
Genetic Map
Chromosome 16
cytoband B1
 
Mapping data( 2)
Sequence Map
Chr16:22381386-22439643 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Protein SuperFamily: transcription factor ER81
TreeFam: TF316214
Sequences
Representative Sequences Length Strain/Species Flank
genomic 104156 NCBI Gene Model | MGI Sequence Detail 58258 C57BL/6J ± Kb
transcript NM_023794 RefSeq | MGI Sequence Detail 3847 -
polypeptide Q9CXC9 UniProt | EBI | MGI Sequence Detail 510 Not Applicable
For the selected sequences
All sequences(23)
Alleles
and
phenotypes 		All alleles(359) : Targeted, knock-out(2) Targeted, other(4) Gene trapped(353)
Homozygous null mice display male infertility, small testes, azoospermia, and fail to spermatogonia. Mice homozygous for a knock-out allele exhibit preaxial polydactyly.
Polymorphisms SNPs within 2kb(247 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process positive regulation of transcription, regulation of branching involved in mammary gland duct morphogenesis...
Component nucleus
Function DNA binding, sequence-specific DNA binding...
External Resources: FuncBase
Expression Literature Summary: (44 records)
Data Summary: Assays (6)    Results (116)    Tissues (98)    Images (20)
Theiler Stages: 2,3,4,5,7,9,11,12,14,15,16,17,19,21,28
  Assay Type Assays   Results
      RT-PCR 1   15
      RNA in situ 5   101
cDNA source data(159)
External Resources: Allen Brain Atlas  GENSAT  GEO 
Molecular
reagents 		All nucleic(160) cDNA(159) Primer pair(1)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000013089
Consensus CDS Project CCDS37299.1
UniGene 155708
DFCI TC1572047
NIA Mouse Gene Index U036911, U055077
Entrez Gene 104156
International Mouse Knockout Project Status Etv5
Protein
domains
InterPro ID Description
IPR000418 Ets
IPR006715 PEA3-type ETS-domain transcription factor, N-terminal
IPR011991 Winged helix repressor DNA-binding
Graphical View of Protein Domain Structure
References
(Earliest) J:42463 Chotteau-Lelievre A et al., "Differential expression patterns of the PEA3 group transcription factors through murine embryonic development." Oncogene 1997 Aug 18;15(8):937-52
(Latest) J:155594 Lu BC et al., "Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis." Nat Genet 2009 Dec;41(12):1295-302
All references(60)
Other
accession IDs 		MGI:1915818, MGI:1923002
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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