Symbol
Name
ID
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Synonyms
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ptc2
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Genetic Map
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Sequence Map
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Mammalian homology
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Sequences
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All sequences(20)
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Alleles and phenotypes
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All alleles(12) :
Targeted, knock-out(1)
Targeted, other(2)
Gene trapped(9)
| Male mice homozygous for a targeted gene disruption display anemia, abnormal red blood cells, enlarged spleens, extramedullary hematopoiesis, and an increased percentage of neutrophils. Most male mice homozygous for another allele display alopecia and skin lesions. |
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Polymorphisms
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SNPs within 2kb(156 from dbSNP Build 128)
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Gene Ontology (GO) classifications
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Expression
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Literature Summary: (42 records)
Data Summary:
Assays (5)
Results (114)
Tissues (82)
Images (56)
Theiler Stages: 19,21,22,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
2 |
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40 |
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In situ reporter (knock in) |
1 |
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58 |
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RNA in situ |
2 |
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16 |
cDNA source data(25)
External Resources:
GENSAT
GEO
ArrayExpress
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Molecular reagents
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All nucleic(32)
Genomic(2)
cDNA(25)
Primer pair(2)
Other(3)
Microarray probesets(2)
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Other database links
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Protein domains
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Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:41710
Takabatake T et al.,
"Hedgehog and patched gene expression in adult ocular tissues."
FEBS Lett 1997 Jun 30;410(2-3):485-9
(Latest)
J:153743
Purcell P et al.,
"Temporomandibular joint formation requires two distinct hedgehog-dependent steps."
Proc Natl Acad Sci U S A 2009 Oct 27;106(43):18297-302
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All references(48)
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