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Gpc4 Gene Detail
 Symbol
Name
ID
Gpc4
glypican 4
MGI:104902

Nomenclature History
Synonyms 9530073D23Rik, K-glypican
Genetic Map
Chromosome X
16.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 5)

Sequence Map
ChrX:49406198-49518429 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Gpc4 ± 2 cM)
Protein SuperFamily: glypican
TreeFam: TF105317
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000017330 VEGA Gene Model | MGI Sequence Detail 112232 C57BL/6J ± Kb
transcript NM_008150 RefSeq | MGI Sequence Detail 2325 C57BL/6
polypeptide P51655 UniProt | EBI | MGI Sequence Detail 557 Not Applicable
For the selected sequences
All sequences(30)
Alleles
and
phenotypes 		All alleles(9) : Gene trapped(9)
Polymorphisms PCR(1) SNPs within 2kb(386 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Component anchored to membrane, extracellular region...
Function heparan sulfate proteoglycan binding
External Resources: FuncBase
Expression Literature Summary: (8 records)
Data Summary: Assays (5)    Results (106)    Tissues (62)    Images (49)
Theiler Stages: 11,12,13,14,15,16,17
  Assay Type Assays   Results
      Western blot 2   4
      RT-PCR 1   1
      RNA in situ 1   95
      Immunohistochemistry 1   6
cDNA source data(21)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(25) cDNA(21) Primer pair(4) Antibodies(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000031119
DoTS DT.101185035, DT.111022063, DT.526694
Consensus CDS Project CCDS30124.1
DFCI TC1581967, TC1620737
NIA Mouse Gene Index U039381, U260239
Entrez Gene 14735
VEGA Gene Model OTTMUSG00000017330
International Mouse Knockout Project Status Gpc4
Protein
domains
InterPro ID Description
IPR001863 Glypican
IPR019803 Glypican, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:28429 Watanabe K et al., "K-glypican: a novel GPI-anchored heparan sulfate proteoglycan that is highly expressed in developing brain and kidney." J Cell Biol 1995 Sep;130(5):1207-18
(Latest) J:153618 Ahrens MJ et al., "Convergent extension movements in growth plate chondrocytes require gpi-anchored cell surface proteins." Development 2009 Oct;136(20):3463-74
All references(22)
Other
accession IDs 		MGD-MRK-29056, MGI:1925872, MGI:2147881, MGI:2147905, MGI:2152785
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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