Symbol
Name
ID
|
|
|
Synonyms
|
CDKI, Kip2, p57Kip2
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(28)
|
Alleles
and
phenotypes
|
All alleles(4) :
Targeted, knock-out(3)
Targeted, other(1)
| Homozygous mutants or heterozygotes with a mutant maternal allele have developmental defects including cleft palate, gastrointestinal defects and short limbs. Most mutants die at birth; survivors are growth retarded and have immature reproductive systems. |
Associated Human Diseases (2)
Alleles Annotated to Human Diseases (2)
|
|
Polymorphisms
|
All PCR and RFLP(2) :
PCR(1)
RFLP(1)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (123 records)
Data Summary:
Assays (32)
Results (244)
Tissues (138)
Images (32)
Theiler Stages: 4,9,11,13,15,17,19,20,21,22,23,24,25,26,28
| |
Assay Type |
Assays |
|
Results |
| |
Western blot |
2 |
|
4 |
| |
RT-PCR |
18 |
|
108 |
| |
RNA in situ |
9 |
|
115 |
| |
Immunohistochemistry |
1 |
|
5 |
| |
Northern blot |
2 |
|
12 |
cDNA source data(186)
External Resources:
Allen Brain Atlas
GENSAT
GEO
|
Molecular
reagents
|
All nucleic(231)
Genomic(24)
cDNA(188)
Primer pair(14)
Other(5)
Antibodies(2)
Microarray probesets(2)
|
Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR003175 |
Cyclin-dependent kinase inhibitor |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:10529
Bastian H et al.,
"A murine even-skipped homologue, Evx 1, is expressed during early embryogenesis and neurogenesis in a biphasic manner [published erratum appears in EMBO J 1991 Dec;10(12):3978]"
EMBO J 1990 Jun;9(6):1839-52
(Latest)
J:153616
Gabory A et al.,
"H19 acts as a trans regulator of the imprinted gene network controlling growth in mice."
Development 2009 Oct;136(20):3413-21
|
All references(157)
|
Other
accession IDs
|
MGD-MRK-25998, MGI:2142098
|
