Symbol
Name
ID
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(19)
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Alleles
and
phenotypes
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All alleles(3) :
Targeted, knock-out(1)
Targeted, other(2)
| Homozygous mutation of this gene results in extensive embryonic lethality and mutants surviving to birth die within the first 2 days of life. The kidneys are small and exhibit delayed development. |
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Polymorphisms
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RFLP(1)
SNPs within 2kb(110 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (80 records)
Data Summary:
Assays (25)
Results (288)
Tissues (223)
Images (72)
Theiler Stages: 1,2,3,4,5,6,8,9,10,11,12,13,14,15,17,18,19,20,21,22,23,24,26,28
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Assay Type |
Assays |
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Results |
| |
RT-PCR |
12 |
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85 |
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RNA in situ |
11 |
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195 |
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Immunohistochemistry |
1 |
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6 |
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RNase protection |
1 |
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2 |
cDNA source data(16)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
|
All nucleic(31)
cDNA(18)
Primer pair(10)
Other(3)
Antibodies(1)
Microarray probesets(2)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR005816 |
Secreted growth factor Wnt protein |
| IPR005817 |
Wnt superfamily |
| IPR018161 |
Secreted growth factor Wnt protein, conserved site |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:21464
Adamson MC et al.,
"Isolation and genetic mapping of two novel members of the murine Wnt gene family, Wnt11 and Wnt12, and the mapping of Wnt5a and Wnt7a."
Genomics 1994 Nov 1;24(1):9-13
(Latest)
J:153202
Gerber SD et al.,
"The murine Fgfrl1 receptor is essential for the development of the metanephric kidney."
Dev Biol 2009 Nov 1;335(1):106-19
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All references(96)
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Other
accession IDs
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MGD-MRK-18782
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