Symbol
Name
ID
|
|
|
Synonyms
|
fxo, IFT88, Oak Ridge polycystic kidneys, orpk, polaris, Tg737, Tg737Rpw, TgN737Rpw, Ttc10
|
|
Genetic Map
|
|
|
Sequence Map
|
|
Mammalian
homology
|
|
|
Sequences
|
All sequences(21)
|
Alleles
and
phenotypes
|
All alleles(7) :
Targeted, knock-out(1)
Targeted, other(2)
Gene trapped(1)
Transgenic(1)
Chemically induced(2)
| Mice homozygous for a null allele display early to mid-gestation lethality, random patterning of the left-right body axis, neural tube defects, pericardial sac expansion, enlarged limb buds, polydactyly, and absent embryonic node cilia. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (1)
|
|
Polymorphisms
|
SNPs within 2kb(267 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (25 records)
Data Summary:
Assays (1)
Results (4)
Tissues (2)
Theiler Stages: 28
| |
Assay Type |
Assays |
|
Results |
| |
Northern blot |
1 |
|
4 |
cDNA source data(33)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(39)
Genomic(6)
cDNA(33)
Microarray probesets(2)
|
Other database
links
|
|
Protein
domains
|
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:18508
Moyer JH et al.,
"Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice."
Science 1994 May 27;264(5163):1329-33
(Latest)
J:154656
Follit JA et al.,
"Characterization of mouse IFT complex B."
Cell Motil Cytoskeleton 2009 Aug;66(8):457-68
|
All references(65)
|
Other
accession IDs
|
MGD-MRK-15052, MGI:2145834
|
Analysis Tools
MGI BioMart
