Symbol
Name
ID
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Synonyms
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cholesterol side chain cleavage, cscc, Cyp11a, D9Ertd411e, P450scc, Scc
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(26)
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Alleles
and
phenotypes
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All alleles(2) :
Targeted, knock-out(1)
Targeted, other(1)
| Homozygous null mice are exhibit a steroid deficiency and die within days of birth showing signs of dehydration. Males are feminized with female external genitalia and underdeveloped gonads. |
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Polymorphisms
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RFLP(1)
SNPs within 2kb(53 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (53 records)
Data Summary:
Assays (9)
Results (84)
Tissues (38)
Images (4)
Theiler Stages: 4,10,18,20,21,22,23,24,25,26,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
6 |
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72 |
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RNA in situ |
3 |
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12 |
cDNA source data(70)
External Resources:
Allen Brain Atlas
GEO
|
Molecular
reagents
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All nucleic(81)
Genomic(1)
cDNA(73)
Primer pair(6)
Other(1)
Microarray probesets(2)
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Pathways
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Other database
links
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Protein
domains
|
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:26017
Perkins LM et al.,
"Quantification of P450scc, P450(17) alpha, and iron sulfur protein reductase in Leydig cells and adrenals of inbred strains of mice."
Endocrinology 1988 Dec;123(6):2675-82
(Latest)
J:152858
Garcia-Ortiz JE et al.,
"Foxl2 functions in sex determination and histogenesis throughout mouse ovary development."
BMC Dev Biol 2009;9():36
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All references(74)
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Other
accession IDs
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MGD-MRK-2291, MGI:1196317
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