Symbol
Name
ID
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Synonyms
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bagpipe, Bax, Nkx-3.1, NKX3.1, NKX3A
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Genetic Map
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Sequence Map
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Mammalian
homology
|
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Sequences
|
All sequences(15)
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Alleles
and
phenotypes
|
All alleles(9) :
Targeted, knock-out(3)
Targeted, other(6)
| Homozygotes for targeted null mutations exhibit reduced minor salivary glands with altered duct morphology, altered prostate ductal morphogenesis, and prostate epithelial hyperplasia and neoplasia. Heterozygotes develop neoplastic foci. |
Associated Human Diseases (1)
Alleles Annotated to Human Diseases (2)
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Polymorphisms
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RFLP(1)
SNPs within 2kb(37 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
|
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Expression
|
Literature Summary: (18 records)
Data Summary:
Assays (5)
Results (54)
Tissues (50)
Images (5)
Theiler Stages: 2,3,4,5,16,17,21,26,28
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Assay Type |
Assays |
|
Results |
| |
RT-PCR |
1 |
|
15 |
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RNA in situ |
4 |
|
39 |
cDNA source data(9)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(14)
Genomic(2)
cDNA(9)
Primer pair(1)
Other(2)
Microarray probesets(2)
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Other database
links
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Protein
domains
|
Graphical View
of Protein Domain Structure
|
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References
|
(Earliest)
J:37120
Bieberich CJ et al.,
"Prostate-specific and androgen-dependent expression of a novel homeobox gene."
J Biol Chem 1996 Dec 13;271(50):31779-82
(Latest)
J:153914
Song H et al.,
"Loss of Nkx3.1 leads to the activation of discrete downstream target genes during prostate tumorigenesis."
Oncogene 2009 Sep 17;28(37):3307-19
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All references(51)
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Other
accession IDs
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MGD-MRK-12894
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Analysis Tools
MGI BioMart
