Symbol
Name
ID
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Synonyms
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[Heparan sulfate]-glucosamine N-sulfotransferase, glucosaminyl N-deacetylase/N-sulphotransferase-2, Mndns
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Genetic Map
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Chromosome 14
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cytoband B
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Mapping data(
1)
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(31)
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Alleles
and
phenotypes
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All alleles(3) :
Targeted, knock-out(3)
| Mice homozugous for a null allele exhibit reduced mast cell numbers, histamine storage, protease storage and degranulation. |
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Polymorphisms
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SNPs within 2kb(22 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
|
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Expression
|
Literature Summary: (6 records)
Data Summary:
Assays (3)
Results (30)
Tissues (18)
Images (2)
Theiler Stages: 10,16,18,20,22,23,25,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
3 |
|
30 |
cDNA source data(47)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(52)
Genomic(4)
cDNA(47)
Primer pair(1)
Microarray probesets(2)
|
Other database
links
|
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Protein
domains
|
| InterPro ID |
Description |
| IPR000863 |
Sulfotransferase domain |
Graphical View
of Protein Domain Structure
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|
References
|
(Earliest)
J:17539
Eriksson I et al.,
"cDNA cloning and sequencing of mouse mastocytoma glucosaminyl N-deacetylase/N-sulfotransferase, an enzyme involved in the biosynthesis of heparin."
J Biol Chem 1994 Apr 8;269(14):10438-43
(Latest)
J:150516
Hu Z et al.,
"NDST1-dependent heparan sulfate regulates BMP signaling and internalization in lung development."
J Cell Sci 2009 Apr 15;122(Pt 8):1145-54
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All references(32)
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Other
accession IDs
|
MGD-MRK-12336
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Analysis Tools
MGI BioMart