Symbol
Name
ID
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Synonyms
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Gb, grizzle-belly, Mgf, SF, Sl, SLF, Steel, Steel factor, stem cell factor
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Genetic Map
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Sequence Map
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Mammalian
homology
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Sequences
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All sequences(38)
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Alleles
and
phenotypes
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All alleles(52) :
Targeted, other(1)
Gene trapped(4)
Spontaneous(18)
Chemically induced(15)
Radiation induced(14)
Other(2)
| Mutations in this gene affect migration of embryonic stem cells and cause similar phenotypes to mutations in its receptor gene (Kit). Mutants show mild to severe defects in pigmentation, hemopoiesis and reproduction. |
Phenotype Images (7)
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Polymorphisms
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RFLP(17)
SNPs within 2kb(680 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
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Literature Summary: (58 records)
Data Summary:
Assays (24)
Results (182)
Tissues (112)
Images (49)
Theiler Stages: 1,2,3,4,5,11,13,14,15,17,18,19,20,21,22,23,24,25,26,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
14 |
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89 |
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RNA in situ |
8 |
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63 |
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Immunohistochemistry |
2 |
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30 |
cDNA source data(99)
External Resources:
Allen Brain Atlas
GENSAT
GEO
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Molecular
reagents
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All nucleic(128)
Genomic(12)
cDNA(103)
Primer pair(8)
Other(5)
Antibodies(1)
Microarray probesets(5)
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Other database
links
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Protein
domains
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| InterPro ID |
Description |
| IPR003452 |
Stem cell factor |
| IPR009079 |
Four-helical cytokine-like, core |
Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:104625
Russell LB et al.,
"Steel (Sl) and Pearl (pe)"
Mouse News Lett 1953;8():14
(Latest)
J:152858
Garcia-Ortiz JE et al.,
"Foxl2 functions in sex determination and histogenesis throughout mouse ovary development."
BMC Dev Biol 2009;9():36
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All references(357)
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Other
accession IDs
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MGD-MRK-10006, MGD-MRK-12219, MGD-MRK-14435, MGD-MRK-2018, MGD-MRK-2093
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