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Mbl2 Gene Detail
 Symbol
Name
ID
Mbl2
mannose-binding lectin (protein C) 2
MGI:96924

Nomenclature History
Synonyms MBL, MBL-C, MBP-C
Genetic Map
Chromosome 19
25.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 7)

Sequence Map
Chr19:30307447-30314172 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Mbl2 ± 2 cM)
Protein SuperFamily: mannose-binding lectin
TreeFam: TF330481
Sequences
Representative Sequences Length Strain/Species Flank
genomic 17195 NCBI Gene Model | MGI Sequence Detail 6726 C57BL/6J ± Kb
transcript NM_010776 RefSeq | MGI Sequence Detail 1069 BALB/c
polypeptide P41317 UniProt | EBI | MGI Sequence Detail 244 Not Applicable
For the selected sequences
All sequences(20)
Alleles
and
phenotypes 		All alleles(2) : Targeted, knock-out(1) Targeted, other(1)
Polymorphisms RFLP(2) SNPs within 2kb(87 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process complement activation, classical pathway, complement activation, lectin pathway...
Component extracellular region, extracellular space...
Function binding, calcium ion binding...
External Resources: FuncBase
Expression Literature Summary: (1 records)
cDNA source data(42)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(45) Genomic(3) cDNA(42)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000024863
DoTS DT.492491
Consensus CDS Project CCDS29742.1
UniGene 30045
DFCI TC1582711
NIA Mouse Gene Index U019365
Entrez Gene 17195
International Mouse Knockout Project Status Mbl2
Protein
domains
InterPro ID Description
IPR001304 C-type lectin
IPR008160 Collagen triple helix repeat
IPR016186 C-type lectin-like
IPR016187 C-type lectin fold
IPR018378 C-type lectin, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:22454 Sastry K et al., "Molecular characterization of the mouse mannose-binding proteins. The mannose-binding protein A but not C is an acute phase reactant." J Immunol 1991 Jul 15;147(2):692-7
(Latest) J:155648 Ruseva M et al., "Mannan-binding lectin deficiency modulates the humoral immune response dependent on the genetic environment." Immunology 2009 Jun;127(2):279-88
All references(35)
Other
accession IDs 		MGD-MRK-12125
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory