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Plin2 Gene Detail
 Symbol
Name
ID
Plin2
perilipin 2
MGI:87920


Nomenclature History
Synonyms Adfp, adipophilin, ADPH, Adrp
Genetic Map
Chromosome 4
38.9 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 6)

Sequence Map
Chr4:86294290-86315964 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Plin2 ± 2 cM)
Protein SuperFamily: lipid droplet-associated protein, perilipin type
TreeFam: TF328397
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000007453 VEGA Gene Model | MGI Sequence Detail 21675 C57BL/6J ± Kb
transcript NM_007408 RefSeq | MGI Sequence Detail 1887 C57BL/6
polypeptide P43883 UniProt | EBI | MGI Sequence Detail 425 Not Applicable
For the selected sequences
All sequences(47)
Alleles
and
phenotypes
All alleles(4) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(2)
Male mice homozygous for one disruption in this gene are infertile while no comment is made regarding fertility for another such allele.
Polymorphisms All PCR and RFLP(2) : PCR(1) RFLP(1) SNPs within 2kb(101 from dbSNP Build 128)   SNPs within 2kb including multiple locations(123)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process lipid storage, long-chain fatty acid transport...
Component cytoplasm, lipid particle...
Function protein binding
External Resources: FuncBase
Expression Literature Summary: (8 records)
Data Summary: Assays (1)    Results (1)    Tissues (1)    Images (1)
Theiler Stages: 22
  Assay Type Assays   Results
      RNA in situ 1   1
cDNA source data(369)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents
All nucleic(382) Genomic(12) cDNA(369) Primer pair(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000028494
DoTS DT.101720511, DT.55104410, DT.97379230, DT.99867312
Consensus CDS Project CCDS18308.1
UniGene 381
DFCI TC1573348, TC1650896
Entrez Gene 11520
VEGA Gene Model OTTMUSG00000007453
International Mouse Knockout Project Status Plin2
Protein
domains
InterPro ID Description
IPR004279 Perilipin
Graphical View of Protein Domain Structure
References
(Earliest) J:2265 Jiang HP et al., "Isolation and characterization of a full-length cDNA coding for an adipose differentiation-related protein." Proc Natl Acad Sci U S A 1992 Sep 1;89(17):7856-60
(Latest) J:151837 Bougneres L et al., "A role for lipid bodies in the cross-presentation of phagocytosed antigens by MHC class I in dendritic cells." Immunity 2009 Aug 21;31(2):232-44
All references(33)
Other
accession IDs
MGD-MRK-1110, MGD-MRK-1154, MGI:2140117

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory