Symbol
Name
ID
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Synonyms
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dematin
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Genetic Map
|
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Sequence Map
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Mammalian
homology
|
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Sequences
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All sequences(40)
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Alleles
and
phenotypes
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All alleles(142) :
Targeted, knock-out(1)
Gene trapped(141)
| Mice homozygous for a targeted mutation display mild anemia and spherocytosis. Mutant erythrocytes are osmotically fragile and show reduced deformability and filterability as well as increased membrane fragmentation and selective loss of spectrin and actin from RBC membrane skeletons and vesicles. |
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Polymorphisms
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RFLP(1)
SNPs within 2kb(186 from dbSNP Build 128)
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Gene Ontology
(GO)
classifications
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Expression
|
Literature Summary: (2 records)
cDNA source data(13)
External Resources:
GENSAT
GEO
ArrayExpress
|
Molecular
reagents
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All nucleic(14)
cDNA(14)
Microarray probesets(2)
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Other database
links
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| Ensembl Gene Model |
ENSMUSG00000022099 |
| DoTS |
DT.101370837, DT.101388029, DT.101388030, DT.488525, DT.91563290, DT.94124384, DT.97381166, DT.99863675 |
| Consensus CDS Project |
CCDS27259.1 |
| DFCI |
TC1577143, TC1588421, TC1592978, TC1608655, TC1624083 |
| NIA Mouse Gene Index |
U035751, U094031 |
| Entrez Gene |
13829 |
| International Mouse Knockout Project Status |
Epb4.9 |
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Protein
domains
|
| InterPro ID |
Description |
| IPR003128 |
Villin headpiece |
Graphical View
of Protein Domain Structure
|
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References
|
(Earliest)
J:25233
Peters LL et al.,
"The gene encoding the erythrocyte membrane skeleton protein dematin (Epb4.9) maps to mouse chromosome 14."
Genomics 1995 Apr 10;26(3):634-5
(Latest)
J:138919
Robledo RF et al.,
"Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice."
Blood 2008 Nov 15;112(10):4298-307
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All references(19)
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Other
accession IDs
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MGD-MRK-16455, MGI:2145622
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Analysis Tools
MGI BioMart
