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Ccl5 Gene Detail
 Symbol
Name
ID
Ccl5
chemokine (C-C motif) ligand 5
MGI:98262


Nomenclature History
Synonyms MuRantes, RANTES, Scya5, SISd, TCP228
Genetic Map
Chromosome 11
47.4 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 7)

Sequence Map
Chr11:83339280-83344020 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat; guinea pig    (Mammalian Orthology)
Comparative Map (Mouse/Human Ccl5 ± 2 cM)
Protein SuperFamily: small inducible chemokine, C/CC types
TreeFam: TF334888
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000000992 VEGA Gene Model | MGI Sequence Detail 4741 C57BL/6J ± Kb
transcript NM_013653 RefSeq | MGI Sequence Detail 579 C57BL/6
polypeptide P30882 UniProt | EBI | MGI Sequence Detail 91 Not Applicable
For the selected sequences
All sequences(27)
Alleles
and
phenotypes
All alleles(1) : Targeted, knock-out(1)
Homozygous mutation of this gene results in decreased ear and footpad swelling following injection with DHT. T cell proliferative response is also impaired in mutant mice.
Polymorphisms SNPs within 2kb(24 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process chemotaxis, immune response...
Component cytoplasm, extracellular region...
Function chemokine activity, cytokine activity...
External Resources: FuncBase
Expression Literature Summary: (1 records)
Data Summary: Assays (3)    Results (22)    Tissues (12)
Theiler Stages: 17,19,20,21,22,23,24,25,26,28
  Assay Type Assays   Results
      RT-PCR 1   7
      Northern blot 2   15
cDNA source data(18)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents
All nucleic(23) Genomic(3) cDNA(18) Primer pair(2)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000035042
DoTS DT.490170, DT.99854861
Consensus CDS Project CCDS36254.1
UniGene 284248
DFCI TC1583383
NIA Mouse Gene Index U033194
Entrez Gene 20304
VEGA Gene Model OTTMUSG00000000992
International Mouse Knockout Project Status Ccl5
Protein
domains
InterPro ID Description
IPR000827 Small chemokine, C-C group, conserved site
IPR001811 Small chemokine, interleukin-8-like
Graphical View of Protein Domain Structure
References
(Earliest) J:17919 Schall TJ et al., "A human T cell-specific molecule is a member of a new gene family." J Immunol 1988 Aug 1;141(3):1018-25
(Latest) J:142395 Kang SJ et al., "Regulation of hierarchical clustering and activation of innate immune cells by dendritic cells." Immunity 2008 Nov;29(5):819-33
All references(41)
Other
accession IDs
MGD-MRK-14336

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory