Symbol
Name
ID
|
|
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Synonyms
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PDGF-B, Sis
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Genetic Map
|
|
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Sequence Map
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Mammalian
homology
|
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Sequences
|
All sequences(32)
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Alleles
and
phenotypes
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All alleles(5) :
Targeted, knock-out(3)
Targeted, other(1)
Gene trapped(1)
| Homozygotes for targeted null mutations exhibit absence of microvascular pericytes, capillary aneurisms, endothelial hyperplasia, edema, hemorrhages, erythroblastosis, macrocytic anemia, thrombocytopenia, kidney defects, and perinatal lethality. |
Phenotype Images (1)
|
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Polymorphisms
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All PCR and RFLP(10) :
PCR(3)
RFLP(7)
SNPs within 2kb(128 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
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Expression
|
Literature Summary: (44 records)
Data Summary:
Assays (4)
Results (21)
Tissues (13)
Images (3)
Theiler Stages: 9,11,13,14,22,23,28
| |
Assay Type |
Assays |
|
Results |
| |
RT-PCR |
1 |
|
4 |
| |
RNA in situ |
1 |
|
1 |
| |
RNase protection |
2 |
|
16 |
cDNA source data(24)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(43)
Genomic(12)
cDNA(24)
Primer pair(4)
Other(3)
Microarray probesets(3)
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Other database
links
|
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Protein
domains
|
| InterPro ID |
Description |
| IPR000072 |
Platelet-derived growth factor (PDGF) |
| IPR006782 |
Platelet-derived growth factor, N-terminal |
| IPR015583 |
Platelet-Derived Growth Factor B Chain |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:6890
Dalla-Favera R et al.,
"Chromosomal localization of the human homolog (c-sis) of the simian sarcoma virus onc gene."
Science 1982 Nov 12;218(4573):686-8
(Latest)
J:152840
Hou SC et al.,
"Ankrd17, an ubiquitously expressed ankyrin factor, is essential for the vascular integrity during embryogenesis."
FEBS Lett 2009 Sep 3;583(17):2765-71
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All references(145)
|
Other
accession IDs
|
MGD-MRK-13212, MGD-MRK-14423
|
Analysis Tools
MGI BioMart
