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Nid1 Gene Detail
 Symbol
Name
ID
Nid1
nidogen 1
MGI:97342

Nomenclature History
STS D13Mit44
Synonyms entactin, entactin 1, entactin-1, nidogen-1
Genetic Map
Chromosome 13
7.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 30)

Sequence Map
Chr13:13529958-13604521 bp, + strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Nid1 ± 2 cM)
Protein SuperFamily: nidogen-1
TreeFam: TF320666
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000005397 Ensembl Gene Model | MGI Sequence Detail 74564 C57BL/6J ± Kb
transcript NM_010917 RefSeq | MGI Sequence Detail 6046 C57BL/6
polypeptide P10493 UniProt | EBI | MGI Sequence Detail 1245 Not Applicable
For the selected sequences
All sequences(27)
Alleles
and
phenotypes 		All alleles(14) : Targeted, knock-out(2) Gene trapped(12)
Polymorphisms RFLP(11) SNPs within 2kb(257 from dbSNP Build 128)   SNPs within 2kb including multiple locations(293)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process bioluminescence, cell adhesion...
Component basement membrane, extracellular region...
Function calcium ion binding, extracellular matrix binding...
External Resources: FuncBase
Expression Literature Summary: (64 records)
Data Summary: Assays (14)    Results (115)    Tissues (94)    Images (18)
Theiler Stages: 11,15,17,18,20,22,23,24,25,26,28
  Assay Type Assays   Results
      RT-PCR 2   50
      RNA in situ 4   27
      Immunohistochemistry 7   28
      Northern blot 1   10
cDNA source data(192)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(228) Genomic(28) cDNA(193) Primer pair(6) Other(1) Antibodies(7)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000005397
DoTS DT.94280402
Consensus CDS Project CCDS26244.1
UniGene 4691
PDB 1GL4, 1H4U, 1NPE
DFCI TC1572194
Entrez Gene 18073
International Mouse Knockout Project Status Nid1
Protein
domains
InterPro ID Description
IPR000033 Low-density lipoprotein receptor, class B (YWTD) repeat
IPR000152 EGF-type aspartate/asparagine hydroxylation site
IPR000716 Thyroglobulin type-1
IPR000742 EGF-like, type 3
IPR001881 EGF-like calcium-binding
IPR003886 Nidogen, extracellular domain
IPR006210 EGF-like
IPR006605 G2 nidogen/fibulin G2F
IPR009017 Green fluorescent protein-like
IPR011042 Six-bladed beta-propeller, TolB-like
IPR013032 EGF-like region, conserved site
IPR013091 EGF calcium-binding
IPR018097 EGF-like calcium-binding, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:34858 Durkin ME et al., "Amino acid sequence and domain structure of entactin. Homology with epidermal growth factor precursor and low density lipoprotein receptor." J Cell Biol 1988 Dec;107(6 Pt 2):2749-56
(Latest) J:154465 Rajagopal R et al., "The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation." Dev Biol 2009 Nov 15;335(2):305-16
All references(99)
Other
accession IDs 		MGD-MRK-12878
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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