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Ndn Gene Detail
 Symbol
Name
ID
Ndn
necdin
MGI:97290


Nomenclature History
Synonyms Peg6
Genetic Map
Chromosome 7
28.0 cM, cytoband C
Detailed Genetic Map ± 1 cM
 
Mapping data( 14)

Sequence Map
Chr7:69493163-69494814 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Ndn ± 2 cM)
Protein SuperFamily: tumor associated protein MAGE
TreeFam: TF328505
Sequences
Representative Sequences Length Strain/Species Flank
genomic 17984 NCBI Gene Model | MGI Sequence Detail 1652 C57BL/6J ± Kb
transcript NM_010882 RefSeq | MGI Sequence Detail 1652 C57BL/6
polypeptide P25233 UniProt | EBI | MGI Sequence Detail 325 Not Applicable
For the selected sequences
All sequences(29)
Alleles
and
phenotypes
All alleles(6) : Targeted, knock-out(3) Targeted, other(3)
Associated Human Diseases (1)   Alleles Annotated to Human Diseases (4)   Phenotype Images (3)  
Polymorphisms All PCR and RFLP(3) : PCR(2) RFLP(1) SNPs within 2kb(24 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process axon extension involved in development, axonal fasciculation...
Component centrosome, cytoplasm...
Function DNA binding, gamma-tubulin binding...
External Resources: FuncBase
Expression Literature Summary: (35 records)
Data Summary: Assays (10)    Results (159)    Tissues (135)    Images (40)
Theiler Stages: 16,20,22,24,25,26,28
  Assay Type Assays   Results
      Western blot 1   7
      RT-PCR 2   12
      RNA in situ 3   115
      Immunohistochemistry 1   2
      Northern blot 3   23
cDNA source data(136)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents
All nucleic(147) Genomic(5) cDNA(137) Primer pair(4) Other(1) Antibodies(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000033585
DoTS DT.535951
Consensus CDS Project CCDS21326.1
UniGene 400253
DFCI TC1571866, TC1675529
NIA Mouse Gene Index U008170
Entrez Gene 17984
International Mouse Knockout Project Status Ndn
Protein
domains
InterPro ID Description
IPR002190 MAGE protein
Graphical View of Protein Domain Structure
References
(Earliest) J:28227 Maruyama K et al., "A novel brain-specific mRNA encoding nuclear protein (necdin) expressed in neurally differentiated embryonal carcinoma cells." Biochem Biophys Res Commun 1991 Jul 15;178(1):291-6
(Latest) J:155490 Kubota Y et al., "Necdin restricts proliferation of hematopoietic stem cells during hematopoietic regeneration." Blood 2009 Nov 12;114(20):4383-92
All references(68)
Other
accession IDs
MGD-MRK-12799, MGI:2141993

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory