Symbol
Name
ID
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Synonyms
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72kDa gelatinase, 72kDa type IV collagenase, Clg4a, GelA, gelatinase A, MMP-2
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Genetic Map
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Sequence Map
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Mammalian homology
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Sequences
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All sequences(65)
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Alleles and phenotypes
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All alleles(1) :
Targeted, knock-out(1)
| Homozygotes for a targeted null mutation exhibit slightly delayed growth, reduced neovascularization, retarded tumor progression, an exaggerated asthma response to allergens, and impaired branching morphogenesis of the mammary gland. |
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Polymorphisms
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RFLP(1)
SNPs within 2kb(246 from dbSNP Build 128)
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Gene Ontology (GO) classifications
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Expression
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Literature Summary: (51 records)
Data Summary:
Assays (8)
Results (23)
Tissues (13)
Images (3)
Theiler Stages: 17,19,20,21,22,23,28
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Assay Type |
Assays |
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Results |
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Western blot |
1 |
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3 |
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RT-PCR |
5 |
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14 |
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RNA in situ |
1 |
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2 |
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Immunohistochemistry |
1 |
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4 |
cDNA source data(171)
External Resources:
Allen Brain Atlas
GENSAT
GEO
ArrayExpress
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Molecular reagents
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All nucleic(177)
cDNA(171)
Primer pair(4)
Other(2)
Antibodies(2)
Microarray probesets(2)
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Other database links
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Protein domains
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Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:218
Bennett D,
"Brain hernia, a new recessive mutation in the mouse"
J Hered 1959;50():265-8
(Latest)
J:155674
Munoz M et al.,
"Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17."
J Exp Med 2009 Dec 21;206(13):3047-59
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All references(151)
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Other accession IDs
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MGD-MRK-12279, MGD-MRK-2013
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