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Mbp Gene Detail
 Symbol
Name
ID
Mbp
myelin basic protein
MGI:96925

Nomenclature History
STS D18Nds1
Synonyms golli-mbp, Hmbpr
Genetic Map
Chromosome 18
55.0 cM, cytoband E2-E4
Detailed Genetic Map ± 1 cM
 
Mapping data( 42)

Sequence Map
Chr18:82644538-82755029 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Mbp ± 2 cM)
TreeFam: TF333391
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000016316 VEGA Gene Model | MGI Sequence Detail 110492 C57BL/6J ± Kb
transcript NM_001025245 RefSeq | MGI Sequence Detail 4820 C57BL/6
polypeptide P04370 UniProt | EBI | MGI Sequence Detail 250 Not Applicable
For the selected sequences
All sequences(150)
Alleles
and
phenotypes 		All alleles(9) : Targeted, knock-out(1) Gene trapped(3) Spontaneous(5)
Phenotype Images (1)  
Polymorphisms All PCR and RFLP(26) : PCR(4) RFLP(22) SNPs within 2kb(197 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process myelination
Component cell projection, cell soma...
Function structural constituent of myelin sheath
External Resources: FuncBase
Expression Literature Summary: (89 records)
Data Summary: Assays (12)    Results (77)    Tissues (19)    Images (13)
Theiler Stages: 20,22,24,26,28
  Assay Type Assays   Results
      Western blot 4   29
      RT-PCR 6   30
      RNA in situ 2   18
cDNA source data(30)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(80) Genomic(18) cDNA(34) Primer pair(10) Other(18) Antibodies(3)
Microarray probesets(6)
Other database
links
Ensembl Gene Model ENSMUSG00000041607
DoTS DT.101405201, DT.101405203, DT.101405206, DT.103584982, DT.110778714, DT.110778883, DT.40179933, DT.525774, DT.94312255, DT.94378179, DT.94378245, DT.94403522, DT.97415796, DT.97415803, DT.97415805, DT.99866450
Consensus CDS Project CCDS29373.1, CCDS29374.1, CCDS29376.1, CCDS29377.1, CCDS29378.1, CCDS29379.1, CCDS37875.1
DFCI TC1573895, TC1582023, TC1583098, TC1585662, TC1587179, TC1587280, TC1589559, TC1596602, TC1602734, TC1773818
NIA Mouse Gene Index U018952
Entrez Gene 17196
VEGA Gene Model OTTMUSG00000016316
International Mouse Knockout Project Status Mbp
Protein
domains
InterPro ID Description
IPR000548 Myelin basic protein
Graphical View of Protein Domain Structure
References
(Earliest) J:46297 Biddle F et al., "The genetic analysis of the sensitivity of the CBA/J strain et al" Mouse News Lett 1973;48():24
(Latest) J:156196 Edgar JM et al., "Early ultrastructural defects of axons and axon-glia junctions in mice lacking expression of Cnp1." Glia 2009 Dec;57(16):1815-24
All references(313)
Other
accession IDs 		MGD-MRK-10746, MGD-MRK-12126, MGD-MRK-12253, MGD-MRK-14404, MGI:2147393, MGI:2147422
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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