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Il7r Gene Detail
 Symbol
Name
ID
Il7r
interleukin 7 receptor
MGI:96562

Nomenclature History
Synonyms CD127, IL-7 receptor alpha chain, IL-7Ralpha
Genetic Map
Chromosome 15
4.6 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 6)

Sequence Map
Chr15:9435914-9459613 bp, - strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; horse; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Il7r ± 2 cM)
Protein SuperFamily: interleukin-7 receptor
TreeFam: TF336573
Sequences
Representative Sequences Length Strain/Species Flank
genomic 16197 NCBI Gene Model | MGI Sequence Detail 23700 C57BL/6J ± Kb
transcript NM_008372 RefSeq | MGI Sequence Detail 3227 C57BL/6
polypeptide P16872 UniProt | EBI | MGI Sequence Detail 459 Not Applicable
For the selected sequences
All sequences(27)
Alleles
and
phenotypes 		All alleles(3) : Targeted, knock-out(2) Targeted, other(1)
Polymorphisms RFLP(1) SNPs within 2kb(153 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process B cell proliferation, cell growth...
Component external side of plasma membrane, integral to membrane...
Function cytokine receptor activity, receptor activity...
External Resources: FuncBase
Expression Literature Summary: (16 records)
Data Summary: Assays (5)    Results (16)    Tissues (12)    Images (1)
Theiler Stages: 4,14,21,22,23,24,25,28
  Assay Type Assays   Results
      RT-PCR 5   16
cDNA source data(144)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(157) Genomic(4) cDNA(147) Primer pair(6)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000003882
DoTS DT.101138300, DT.521789, DT.87068859, DT.94230833
Consensus CDS Project CCDS27376.1
UniGene 389
DFCI TC1574987, TC1753212
NIA Mouse Gene Index U036001
Entrez Gene 16197
International Mouse Knockout Project Status Il7r
Protein
domains
InterPro ID Description
IPR003531 Short hematopoietin receptor, family 1, conserved site
IPR003961 Fibronectin, type III
IPR008957 Fibronectin, type III-like fold
Graphical View of Protein Domain Structure
References
(Earliest) J:10373 Goodwin RG et al., "Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily." Cell 1990 Mar 23;60(6):941-51
(Latest) J:154064 Nagatake T et al., "Id2-, RORgammat-, and LTbetaR-independent initiation of lymphoid organogenesis in ocular immunity." J Exp Med 2009 Oct 26;206(11):2351-64
All references(137)
Other
accession IDs 		MGD-MRK-11395
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory