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Il1r2 Gene Detail
 Symbol
Name
ID
Il1r2
interleukin 1 receptor, type II
MGI:96546

Nomenclature History
Synonyms CD121b, IL-1 receptor beta chain, Il1r-2
Genetic Map
Chromosome 1
19.5 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 4)

Sequence Map
Chr1:40141613-40182070 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Il1r2 ± 2 cM)
TreeFam: TF325519
Sequences
Representative Sequences Length Strain/Species Flank
genomic 16178 NCBI Gene Model | MGI Sequence Detail 40458 C57BL/6J ± Kb
transcript NM_010555 RefSeq | MGI Sequence Detail 1360 -
polypeptide P27931 UniProt | EBI | MGI Sequence Detail 410 Not Applicable
For the selected sequences
All sequences(16)
Alleles
and
phenotypes 		All alleles(1) : Targeted, knock-out(1)
Polymorphisms RFLP(1) SNPs within 2kb(267 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Component integral to membrane, membrane...
Function interleukin-1 receptor activity, interleukin-1, Type II, blocking receptor activity...
External Resources: FuncBase
Expression Literature Summary: (2 records)
Data Summary: Assays (2)    Results (14)    Tissues (11)
Theiler Stages: 17,19,20
  Assay Type Assays   Results
      RT-PCR 2   14
cDNA source data(15)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(16) cDNA(15) Primer pair(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000026073
DoTS DT.489118, DT.91575131
Consensus CDS Project CCDS14909.1
UniGene 1349
DFCI TC1584154, TC1596098
NIA Mouse Gene Index U000194
Entrez Gene 16178
International Mouse Knockout Project Status Il1r2
Protein
domains
InterPro ID Description
IPR003599 Immunoglobulin subtype
IPR004074 Interleukin-1 receptor, type I/II
IPR004077 Interleukin-1 receptor, type II
IPR007110 Immunoglobulin-like
IPR013151 Immunoglobulin
IPR013783 Immunoglobulin-like fold
IPR015621 Interleukin-1 receptor
Graphical View of Protein Domain Structure
References
(Earliest) J:14586 Chizzonite R et al., "Two high-affinity interleukin 1 receptors represent separate gene products." Proc Natl Acad Sci U S A 1989 Oct;86(20):8029-33
(Latest) J:143615 Orelio C et al., "Interleukin-1-mediated hematopoietic cell regulation in the aorta-gonad-mesonephros region of the mouse embryo." Blood 2008 Dec 15;112(13):4895-904
All references(24)
Other
accession IDs 		MGD-MRK-11370, MGD-MRK-11372
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory