About   Help   FAQ
Tour our new Quick Search
Igh-6 Gene Detail
 Symbol
Name
ID
Igh-6
immunoglobulin heavy chain 6 (heavy chain of IgM)
MGI:96448

Nomenclature History
STS D12Mit8
Synonyms BCR, Ig mu, Igh-M, Igh6, IgM, muH, muMT
Genetic Map
Chromosome 12
58.0 cM, cytoband F1-2
Detailed Genetic Map ± 1 cM
 
Mapping data( 5)

Sequence Map
Chr12:114657161-114660941 bp, - strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human    (Mammalian Orthology)
Comparative Map (Mouse/Human Igh-6 ± 2 cM)
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000076617 Ensembl Gene Model | MGI Sequence Detail 3781 C57BL/6J ± Kb
transcript BC053409 GenBank | EMBL | DDBJ | MGI Sequence Detail 2172 C57BL/6NCr
polypeptide P01873 UniProt | EBI | MGI Sequence Detail 475 Not Applicable
For the selected sequences
All sequences(84)
Alleles
and
phenotypes 		All alleles(12) : Targeted, knock-out(8) Targeted, other(4)
Associated Human Diseases (1)   Alleles Annotated to Human Diseases (1)  
Polymorphisms All PCR and RFLP(8) : PCR(2) RFLP(6) SNPs within 2kb(37 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process activation of MAPK activity, antigen processing and presentation...
Component B cell receptor complex, external side of plasma membrane...
Function antigen binding, protein binding...
External Resources: FuncBase
Expression Literature Summary: (4 records)
Data Summary: Assays (3)    Results (31)    Tissues (11)
Theiler Stages: 16,21,22,24,25,26,28
  Assay Type Assays   Results
      Western blot 1   9
      Northern blot 2   22
cDNA source data(14)
External Resources: GEO  ArrayExpress 
Molecular
reagents 		All nucleic(104) Genomic(36) cDNA(63) Primer pair(3) Other(2) Antibodies(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000076617
PDB 1I8M
Entrez Gene 16019
International Mouse Knockout Project Status Igh-6
Protein
domains
InterPro ID Description
IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
IPR003596 Immunoglobulin V-set, subgroup
IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like
IPR013106 Immunoglobulin V-set
IPR013783 Immunoglobulin-like fold
Graphical View of Protein Domain Structure
References
(Earliest) J:5763 Warner NL et al., "Allotypes of mouse IgM immunoglobulin." Nature 1977 Feb 3;265(5593):447-9
(Latest) J:156318 Corcos D et al., "Immunoglobulin aggregation leading to Russell body formation is prevented by the antibody light chain." Blood 2010 Jan 14;115(2):282-8
All references(477)
Other
accession IDs 		MGD-MRK-11245, MGD-MRK-11260, MGI:2144796
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory