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H2-DMb2 Gene Detail
 Symbol
Name
ID
H2-DMb2
histocompatibility 2, class II, locus Mb2
MGI:95923

Nomenclature History
Synonyms H-2Mb2, H2-Mb2
Genetic Map
Chromosome 17
18.57 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 2)

Sequence Map
Chr17:34282258-34288498 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
Protein SuperFamily: class II histocompatibility antigen
TreeFam: TF335727
Sequences
Representative Sequences Length Strain/Species Flank
genomic 15000 NCBI Gene Model | MGI Sequence Detail 6241 C57BL/6J ± Kb
transcript NM_010388 RefSeq | MGI Sequence Detail 786 C57BL/6
polypeptide NP_034518 RefSeq | MGI Sequence Detail 261 C57BL/6
For the selected sequences
All sequences(53)
Polymorphisms SNPs within 2kb(105 from dbSNP Build 128)   SNPs within 2kb including multiple locations(115)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class II...
Component endosome membrane, integral to membrane...
Function protein binding
External Resources: FuncBase
Expression cDNA source data(20)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(26) Genomic(5) cDNA(21)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000037548
DoTS DT.101382440, DT.99855840
Consensus CDS Project CCDS37580.1
UniGene 195060
PDB 1K8I
Entrez Gene 15000
International Mouse Knockout Project Status H2-DMb2
Protein
domains
InterPro ID Description
IPR000353 MHC class II, beta chain, N-terminal
IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like
IPR011162 MHC classes I/II-like antigen recognition protein
IPR013783 Immunoglobulin-like fold
IPR014745 MHC class II, alpha/beta chain, N-terminal
References
(Earliest) J:10067 Strathmann M et al., "Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse." Proc Natl Acad Sci U S A 1989 Oct;86(19):7407-9
(Latest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), "The Transcriptional Landscape of the Mammalian Genome" Science 2005;309(5740):1559-1563
All references(13)
Other
accession IDs 		MGD-MRK-10407, MGD-MRK-10519
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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