Symbol
Name
ID
|
|
|
STS
|
DXCch5
|
|
Synonyms
|
Gata-1, Gf-1
|
|
Genetic Map
|
|
|
Sequence Map
|
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Mammalian
homology
|
|
|
Sequences
|
All sequences(18)
|
Alleles
and
phenotypes
|
All alleles(15) :
Targeted, knock-out(4)
Targeted, other(9)
Gene trapped(1)
Chemically induced(1)
| Mutation of this locus affects hematopoiesis. Most hemizygous mutant males mice die at mid-gestation and exhibit blocked erythroid development. Female null and hypomorphic mutants survive birth but exhibit varying degrees of anemia and impaired hematopoiesis. |
Phenotype Images (4)
|
|
Polymorphisms
|
RFLP(9)
SNPs within 2kb(73 from dbSNP Build 128)
|
Gene Ontology
(GO)
classifications
|
|
|
Expression
|
Literature Summary: (67 records)
Data Summary:
Assays (27)
Results (300)
Tissues (210)
Images (30)
Theiler Stages: 2,3,4,5,9,10,11,12,13,14,15,16,17,18,19,20,21,22,28
| |
Assay Type |
Assays |
|
Results |
| |
Western blot |
1 |
|
3 |
| |
RT-PCR |
18 |
|
137 |
| |
RNA in situ |
6 |
|
141 |
| |
Northern blot |
2 |
|
19 |
cDNA source data(27)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
|
Molecular
reagents
|
All nucleic(53)
Genomic(6)
cDNA(29)
Primer pair(15)
Other(3)
Antibodies(1)
Microarray probesets(2)
|
Other database
links
|
|
Protein
domains
|
| InterPro ID |
Description |
| IPR000679 |
Zinc finger, GATA-type |
| IPR013088 |
Zinc finger, NHR/GATA-type |
| IPR016374 |
Transcription factor, GATA-1/2/3 |
Graphical View
of Protein Domain Structure
|
|
References
|
(Earliest)
J:9808
Tsai SF et al.,
"Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells."
Nature 1989 Jun 8;339(6224):446-51
(Latest)
J:155476
Gandillet A et al.,
"Sox7-sustained expression alters the balance between proliferation and differentiation of hematopoietic progenitors at the onset of blood specification."
Blood 2009 Nov 26;114(23):4813-22
|
All references(198)
|
Other
accession IDs
|
MGD-MRK-10002, MGD-MRK-10054, MGD-MRK-9998
|
Analysis Tools
MGI BioMart
