About   Help   FAQ
Tour our new Quick Search
Gabrr2 Gene Detail
 Symbol
Name
ID
Gabrr2
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
MGI:95626

Nomenclature History
Genetic Map
Chromosome 4
10.5 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 6)

Sequence Map
Chr4:33149974-33182840 bp, + strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Gabrr2 ± 2 cM)
Protein SuperFamily: acetylcholine receptor
TreeFam: TF315453
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000004918 VEGA Gene Model | MGI Sequence Detail 32867 C57BL/6J ± Kb
transcript NM_008076 RefSeq | MGI Sequence Detail 1835 C57BL/6
polypeptide P56476 UniProt | EBI | MGI Sequence Detail 465 Not Applicable
For the selected sequences
All sequences(18)
Alleles
and
phenotypes 		All alleles(2) : Targeted, other(2)
Polymorphisms RFLP(2) SNPs within 2kb(116 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (25 annotations)
Process chloride transport, gamma-aminobutyric acid signaling pathway...
Component axon, cell junction...
Function chloride channel activity, chloride ion binding...
External Resources: FuncBase
Expression Literature Summary: (2 records)
Data Summary: Assays (3)    Results (23)    Tissues (3)
Theiler Stages: 23,26,28
  Assay Type Assays   Results
      RT-PCR 3   23
cDNA source data(7)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(9) cDNA(7) Primer pair(1) Other(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000023267
DoTS DT.101165182, DT.40182495
Consensus CDS Project CCDS18020.1
UniGene 6227
DFCI TC1588361
NIA Mouse Gene Index U004172
Entrez Gene 14409
VEGA Gene Model OTTMUSG00000004918
International Mouse Knockout Project Status Gabrr2
Protein
domains
InterPro ID Description
IPR006028 Gamma-aminobutyric acid A receptor
IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
IPR006201 Neurotransmitter-gated ion-channel
IPR006202 Neurotransmitter-gated ion-channel ligand-binding
IPR008057 Gamma-aminobutyric-acid A receptor, Rho
IPR008059 Gamma-aminobutyric-acid A receptor, Rho2
IPR018000 Neurotransmitter-gated ion-channel, conserved site
Graphical View of Protein Domain Structure
References
(Earliest) J:2295 Cutting GR et al., "Identification of a putative gamma-aminobutyric acid (GABA) receptor subunit rho2 cDNA and colocalization of the genes encoding rho2 (GABRR2) and rho1 (GABRR1) to human chromosome 6q14-q21 and mouse chromosome 4." Genomics 1992 Apr;12(4):801-6
(Latest) J:135820 Rose M et al., "PNUTS forms a trimeric protein complex with GABA(C) receptors and protein phosphatase 1." Mol Cell Neurosci 2008 Apr;37(4):808-19
All references(12)
Other
accession IDs 		MGD-MRK-9945
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory