Symbol
Name
ID
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Synonyms
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C3DR, CD21, CD35, Cr-1, Cr-2, Cr1
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Genetic Map
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Sequence Map
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Mammalian homology
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Sequences
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All sequences(28)
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Alleles and phenotypes
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All alleles(5) :
Targeted, knock-out(4)
Targeted, other(1)
| Homozygotes for targeted null mutations exhibit impaired humoral immune responses to T cell-dependent antigens, with limited affinity maturation, and reduced memory B cell and germinal center formation. |
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Polymorphisms
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All PCR and RFLP(3) :
PCR(1)
RFLP(2)
SNPs within 2kb(153 from dbSNP Build 128)
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Gene Ontology (GO) classifications
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Expression
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Literature Summary: (3 records)
Data Summary:
Assays (1)
Results (42)
Tissues (31)
Theiler Stages: 16,18,20,21,23,25,28
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Assay Type |
Assays |
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Results |
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RT-PCR |
1 |
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42 |
cDNA source data(35)
External Resources:
Allen Brain Atlas
GEO
ArrayExpress
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Molecular reagents
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All nucleic(51)
Genomic(12)
cDNA(36)
Primer pair(2)
Other(1)
Microarray probesets(2)
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Other database links
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Protein domains
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Graphical View
of Protein Domain Structure
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References
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(Earliest)
J:7312
Bubbers JE,
"Identification and linkage analyses of a gene, Rcs-1, suppressing spontaneous SJL/J lymphoma expression."
J Natl Cancer Inst 1984 Feb;72(2):441-6
(Latest)
J:155241
Roundy KM et al.,
"Deletion of putative intronic control sequences does not alter cell or stage specific expression of Cr2."
Mol Immunol 2009 Dec;47(2-3):517-25
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All references(110)
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Other accession IDs
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MGD-MRK-2122, MGD-MRK-2123, MGD-MRK-2124, MGD-MRK-2125
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