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Cd5 Gene Detail
 Symbol
Name
ID
Cd5
CD5 antigen
MGI:88340


Nomenclature History
Synonyms Ly-1, Ly-12, Ly-A, Lyt-1
Genetic Map
Chromosome 19
5.0 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 64)

Sequence Map
Chr19:10792639-10813412 bp, - strand
(From Ensembl annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Cd5 ± 2 cM)
Protein SuperFamily: T-cell surface glycoprotein CD5
TreeFam: TF329295
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000024669 Ensembl Gene Model | MGI Sequence Detail 20774 C57BL/6J ± Kb
transcript NM_007650 RefSeq | MGI Sequence Detail 2069 C57BL/6
polypeptide P13379 UniProt | EBI | MGI Sequence Detail 494 Not Applicable
For the selected sequences
All sequences(20)
Alleles
and
phenotypes
All alleles(1) : Targeted, knock-out(1)
Homozygous mutation of this gene does not result in a phenotype.
Polymorphisms RFLP(4) SNPs within 2kb(188 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process induction of apoptosis by extracellular signals, T cell costimulation...
Component external side of plasma membrane, integral to membrane...
Function protein binding, scavenger receptor activity...
External Resources: FuncBase
Expression Literature Summary: (2 records)
Data Summary: Assays (1)    Results (1)    Tissues (1)
Theiler Stages: 28
  Assay Type Assays   Results
      Immunohistochemistry 1   1
cDNA source data(18)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents
All nucleic(22) Genomic(2) cDNA(18) Primer pair(1) Other(1) Antibodies(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000024669
DoTS DT.97392241
Consensus CDS Project CCDS29586.1
UniGene 779
DFCI TC1582750
NIA Mouse Gene Index U038810
Entrez Gene 12507
International Mouse Knockout Project Status Cd5
Protein
domains
InterPro ID Description
IPR001190 Speract/scavenger receptor
IPR003566 T-cell surface glycoprotein CD5
IPR017448 Speract/scavenger receptor related
Graphical View of Protein Domain Structure
References
(Earliest) J:5195 Itakura K et al., "Linkage groups of the theta and Ly-A loci." Nat New Biol 1971 Mar 24;230(12):126
(Latest) J:151986 Ordonez-Rueda D et al., "Increased numbers of thymic and peripheral CD4+ CD25+Foxp3+ cells in the absence of CD5 signaling." Eur J Immunol 2009 Aug;39(8):2233-47
All references(100)
Other
accession IDs
MGD-MRK-11947, MGD-MRK-11950, MGD-MRK-12073, MGD-MRK-1866

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/06/2010
MGI_4.32
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The Jackson Laboratory