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Cd2 Gene Detail
 Symbol
Name
ID
Cd2
CD2 antigen
MGI:88320

Nomenclature History
Synonyms LFA-2, Ly-37, Ly37
Genetic Map
Chromosome 3
48.2 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 13)

Sequence Map
Chr3:101079822-101091862 bp, - strand
(From VEGA annotation of NCBI Build 37)
VEGA ContigView | Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Cd2 ± 2 cM)
Protein SuperFamily: T-cell surface glycoprotein CD2
TreeFam: TF335971
Sequences
Representative Sequences Length Strain/Species Flank
genomic OTTMUSG00000007104 VEGA Gene Model | MGI Sequence Detail 12041 C57BL/6J ± Kb
transcript NM_013486 RefSeq | MGI Sequence Detail 1144 C57BL/6
polypeptide P08920 UniProt | EBI | MGI Sequence Detail 344 Not Applicable
For the selected sequences
All sequences(33)
Alleles
and
phenotypes 		All alleles(3) : Targeted, knock-out(1) Gene trapped(2)
Homozygous mutation of this gene does not appear to result in a phenotype.
Polymorphisms RFLP(4) SNPs within 2kb(94 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process cell adhesion
Component anchored to plasma membrane, external side of plasma membrane...
Function eukaryotic cell surface binding, protein binding...
External Resources: FuncBase
Expression Literature Summary: (1 records)
Data Summary: Assays (1)    Results (46)    Tissues (45)    Images (1)
Theiler Stages: 23,28
  Assay Type Assays   Results
      RT-PCR 1   46
cDNA source data(25)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(33) Genomic(4) cDNA(27) Primer pair(2)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000027863
DoTS DT.40183767, DT.91326861
Consensus CDS Project CCDS17681.1
UniGene 22842
DFCI TC1584332, TC1602781
NIA Mouse Gene Index U024434
Entrez Gene 12481
VEGA Gene Model OTTMUSG00000007104
International Mouse Knockout Project Status Cd2
Protein
domains
InterPro ID Description
IPR008424 Immunoglobulin C2-set
IPR013106 Immunoglobulin V-set
IPR013285 T-cell surface antigen CD2
IPR013783 Immunoglobulin-like fold
IPR015631 Signalling lymphocyte activation molecule
IPR015632 T-cell adhesion molecule CD2
Graphical View of Protein Domain Structure
References
(Earliest) J:8607 Williams AF et al., "Similarities in sequences and cellular expression between rat CD2 and CD4 antigens." J Exp Med 1987 Feb 1;165(2):368-80
(Latest) J:154885 Clarkson NG et al., "Inhibition and activation by CD244 depends on CD2 and phospholipase C-gamma1." J Biol Chem 2009 Sep 11;284(37):24725-34
All references(46)
Other
accession IDs 		MGD-MRK-11978, MGD-MRK-1837
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
Web browser compatibility 		The Jackson Laboratory