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Hsh2d Gene Detail
 Symbol
Name
ID
Hsh2d
hematopoietic SH2 domain containing
MGI:2676364

Nomenclature History
Synonyms ALX, Hsh2
Genetic Map
Chromosome 8
Syntenic
 
Mapping data( 1)
Sequence Map
Chr8:74713567-74724857 bp, + strand
(From NCBI annotation of NCBI Build 37)
Ensembl ContigView | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic    (Mammalian Orthology)
TreeFam: TF336893
Sequences
Representative Sequences Length Strain/Species Flank
genomic 209488 NCBI Gene Model | MGI Sequence Detail 11291 C57BL/6J ± Kb
transcript NM_197944 RefSeq | MGI Sequence Detail 1225 C57BL/6
polypeptide Q6VYH9 UniProt | EBI | MGI Sequence Detail 334 Not Applicable
For the selected sequences
All sequences(11)
Alleles
and
phenotypes 		All alleles(1) : Targeted, knock-out(1)
Polymorphisms SNPs within 2kb(72 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process T cell activation
Component cytoplasm, mitochondrion...
Function protein binding, SH3/SH2 adaptor activity...
External Resources: FuncBase
Expression Literature Summary: (1 records)
Data Summary: Assays (1)    Results (12)    Tissues (12)    Images (1)
Theiler Stages: 16,17,18,28
  Assay Type Assays   Results
      Northern blot 1   12
cDNA source data(9)
External Resources: Allen Brain Atlas  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(9) cDNA(9)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000062007
DoTS DT.55268638
Consensus CDS Project CCDS22410.1
UniGene 157431
DFCI TC1589412
NIA Mouse Gene Index U009484
Entrez Gene 209488
International Mouse Knockout Project Status Hsh2d
Protein
domains
InterPro ID Description
IPR000980 SH2 motif
Graphical View of Protein Domain Structure
References
(Earliest) J:85736 Greene TA et al., "Cloning and characterization of ALX, an adaptor downstream of CD28." J Biol Chem 2003 Nov 14;278(46):45128-34
(Latest) J:149941 Perchonock CE et al., "The related adaptors, adaptor in lymphocytes of unknown function X and Rlk/Itk-binding protein, have nonredundant functions in lymphocytes." J Immunol 2007 Aug 1;179(3):1768-75
All references(6)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/06/2010
MGI_4.32
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